Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Reissue Patent
2000-06-06
2009-08-18
Jiang, Dong (Department: 1646)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
C530S308000, C530S300000, C514S252010
Reissue Patent
active
RE040876
ABSTRACT:
Thiazolidinedione (TZD) and its pharmacologically active derivatives can be used in combination with agonists of glucagon-like peptide-1 (GLP-1), to treat non-insulin dependent diabetes mellitus, optionally with other therapies, by improving glycemic control while minimizing side effects, such as heart hypertrophy and elevated fed-state plasma glucose, which are associated with both TZD and GLP-1 monotherapies. Thus, the co-administration of TZD and GLP-1 helps regulate glucose homeostasis in Type II diabetic patients.
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Johnson William Terry
Stramm Lawrence Edward
Vignati Louis
Yakubu-Madus Fatima Emitsel
Cox Gregory A.
Eli Lilly and Company
Geppert Caren D.
Jiang Dong
Stewart Mark J.
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