Method for treating nerve injury pain associated with shingles

Details Method for treating nerve injury pain associated with shingles Method for treating nerve injury pain associated with shingles

1996-12-23

1998-01-20

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Wearing apparel, fabric, or cloth

424443, 424445, 424447, 424449, A61K 970

Patent

active

057098697

ABSTRACT:
Methods and compositions are offered for reducing nerve injury pain associated with shingles (herpes-zoster and post-herpetic neuralgia), where intradermal delivery of lidocaine is maintained for a predetermined period of time. The lidocaine appears to specifically affect the damaged nerve fibers, while leaving the undamaged and normal nerve fibers with retention of response to other stimuli. Lidocaine formulations are provided which allow for the necessary dosage of the lidocaine in the dermis during the period of treatment. The formulation may be covered with an occlusive or non-occlusive dressing, which protects the lidocaine formulation from mechanical removal and enhances the transport of the lidocaine into the dermis. Long term relief is realized after maintenance of the administration of lidocaine has been terminated.

REFERENCES:
patent: 5589180 (1996-12-01), Hind
patent: 5601838 (1997-02-01), Hind

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