Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Patent
1998-03-10
2000-08-01
Crouch, Deborah
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
A61K 4800
Patent
active
060967218
ABSTRACT:
Methods for treating mucositis are presented. An effective amount of DNA is administered to a patient with mucositis sublingually in a manner that does not cause gene transfer but does cause a reduction in viscosity of mucous or sputum.
REFERENCES:
patent: 5240846 (1993-08-01), Collins et al.
patent: 5292498 (1994-03-01), Boucher, Jr.
patent: 5420116 (1995-05-01), Puchelle et al.
patent: 5470838 (1995-11-01), von Borstel et al.
patent: 5726160 (1998-03-01), McMichael
Canonico, A.E. et al., "Expression of a CMV Promoter Driven Human .alpha.-1 Antitrypsin Gene in Cultured Lung Endothelial Cells and in the Lungs of Rabbits," Clin Res., 39(2): 219A (1991).
Ledley, F.D., "Non-viral gene therapy," Current Opinion in Biotechnology, 5:626-636 (1994).
Ledley, F.D., "Nonviral Gene Therapy: The Promise of Genes as Pharmaceutical Products," Human Gene Therapy, 6: 1129-1144 (Sep., 1995).
Marshall, E., "Gene Therapy's Growing Pains," Science, 269: 1050-1055 (Aug. 25, 1995).
Rosenfeld, M.A. et al., "Adenovirus-Mediated Transfer of a Recombinant .alpha.1-Antitrypsin Gene to the Lung Epithelium in Vivo," Science, 252: 431-434 (Apr. 19, 1991).
Aalton, E.W.F.W. et al., "Noninvasive liposome-mediated gene delivery can correct the ion transport defect in cystic fibrosis mutant mice," Chemical Abstracts, 119(21):62 (Nov. 22, 1993) (Abstract 217089w).
Flotte, T.R., et al., "Stable in vivo expression of the cystic fibrosis transmembrane conductance regulator with an adeno-associated virus vector," Chemical Abstracts, 120(5):229 (Jan. 31, 1994) (Abstract 46918e).
Baker, R.C., "Pitfalls in Diagnosing Acute Otitis Media," Pediatric Annals,20:591-593, 596-598 (Nov., 1991).
Berman, S., "Otitis Media in Developing Countries," Pediatrics, 96(1):126-131 (Jul., 1995).
Dagan, R. et al., "Treatment Failures in Otitis Media--What Can We Learn, " Ear, Nose and Throat J., 77(6 Suppl):16-21 (Jun. 1998).
Karver, S.B., "Otitis Media," Ear, Nose and Throat Disorders, 25(3):619-632 (Sep., 1998).
Klein, J.O., "Otitis Media," Clinical Infectious Disease, 19:823-833 (1994).
Rosenfeld, J. et al., "Acute Otitis Media in Children," Primary Care; Clinics in Office Practice, 23(4):677-686 (Dec. 1996).
Textbook or Respiratory Medicine, John F. Murray, ed., W.B. Saunders Company, Philadelphia, Pa., p. 1038. 1988.
Crouch Deborah
Milkhaus Laboratory, Inc.
Wilson Michael C.
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