Drug – bio-affecting and body treating compositions – Inorganic active ingredient containing – Heavy metal or compound thereof
Reexamination Certificate
2011-01-25
2011-01-25
Arnold, Ernst V (Department: 1613)
Drug, bio-affecting and body treating compositions
Inorganic active ingredient containing
Heavy metal or compound thereof
C424S718000
Reexamination Certificate
active
07875297
ABSTRACT:
A delivery vehicle for a silver ion source such as silver nitrate and the like, suitable for use in the treatment of menorrhagia, comprises a plurality of physiologically inert beads bearing a tissue cauterizing amount of a silver ion source. Preferably the beads are made of a physiologically inert polymer, ceramic or stainless steel. The silver ion source preferably is silver nitrate and can be substantially pure silver nitrate, or can comprise silver nitrate in combination with a physiologically tolerable binder or a diluent. Suitable binders include physiologically tolerable synthetic polymeric binders, polysaccharide binders, and the like. Diluents can include other salt materials such as potassium nitrate. The beads are useful in treating menorrhagia of a mammalian uterus. The beads can be delivered to the uterus via a catheter, and are distributed throughout the uterine cavity by uterine massage or like expedient. Silver ions are delivered to the endometrium and cause necrosis of the endometrial tissue. The silver ions remaining within the uterine cavity can then be neutralized with a sodium chloride solution delivered to the uterus e.g., by catheter, and the beads recovered from the uterus.
REFERENCES:
patent: 3930000 (1975-12-01), Margraf
patent: 5073365 (1991-12-01), Katz et al.
patent: 5891457 (1999-04-01), Neuwirth
patent: 6187346 (2001-02-01), Neuwirth
Solubility Table [online] retrieved from http://en.wikipedia.org/wiki/solubility—table on Aug. 20, 2007; 4 pages.
Ablation Products LLC
Arnold Ernst V
Olson & Cepuritis, Ltd.
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