Method for treating late phase allergic reactions and inflammato

Details Method for treating late phase allergic reactions and inflammato Method for treating late phase allergic reactions and inflammato

1997-08-04

1999-11-09

Bawa, Raj

Drug, bio-affecting and body treating compositions

Effervescent or pressurized fluid containing

Organic pressurized fluid

424 46, 514 56, 514826, 514851, A61K 912

Patent

active

059808659

ABSTRACT:
A method of treating a mammalian patient suffering from or prone to a condition characterized by late phase allergic reactions, airway hyperresponsiveness or inflammatory reactions, e.g., asthma, allergic rhinitis, allergic dermatitis, allergic conjunctivitis, inflammatory bowel disease or rheumatoid arthritis, comprising the administration to the patient of an oral, parenteral, intrabronchial, topical, intranasal or intraocular pharmaceutical composition containing in each dose about 0.005 to about 1.0 mg per kilogram of patient body weight of ultra-low molecular weight heparins (ULMWH) or other sulfated polysaccharides having average molecular weights of about 1,000-3,000 daltons. Suitable inhalant and other pharmaceutical compositions for use in the novel treatment method are also disclosed.

REFERENCES:
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Karnovsky et al., Airwaves and Vascular Remodelling, pp. 45-69 (1994).
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Lemanske et al., "Late Phase Allergic Reactions" in Allergies, Principles and Practice, Mosby Yearbook, Inc., 4th ed. (1997).

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