Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Structurally-modified antibody – immunoglobulin – or fragment...
Reexamination Certificate
2005-04-19
2005-04-19
Mosher, Mary E. (Department: 1648)
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
Structurally-modified antibody, immunoglobulin, or fragment...
C424S141100, C424S143100
Reexamination Certificate
active
06881407
ABSTRACT:
Hepatitis can be treated by administering to a patient in need thereof an effective amount of a compound that neutralizes the effects of secreted TNFalpha. Two types of these compounds are extracellular ligand binding proteins of the human p75 TNF receptor, such as etanercept (Enbrel), and humanized monoclonal antibodies that neutralize the activity of TNFalpha, such as inflixamab (Remicade).
REFERENCES:
patent: 5629285 (1997-05-01), Black et al.
patent: 5641751 (1997-06-01), Heavner
patent: 5698195 (1997-12-01), Le et al.
patent: 5939423 (1999-08-01), Karlin et al.
patent: WO 9822137 (1998-05-01), None
Peterson et al. Annals of the Rheumatic Diseases 62(11):1078-1082 (Nov. 2003, not available as prior art). PDF version provided; best available copy is nearly illegible.*
Peterson et al. Annals of the Rheumatic Diseases 62(11):1078-1082 (Nov. 2003, not available as prior art).Full-text version provided from http://gateway.proquest.com/openurl?url_ver=Z39.88- 2004&res_dat=xri:pqd&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&genr.*
Ohta et al, J. Immunol. 165(2): 956-961, 2000.*
Peterson et al., Safety of TNF-α Antagonists in Patients with Rheumatoid Arthritis and Chronic Hepatitis C. Arthritis Rheum. 44(9), Suppl., Nov. 2001, p. S78.*
Tilg et al., Anti-tumor necrosis factor monoclonal antibody therapy in HCV-positive severe alcoholic hepatitis. Hepatology vol. 34, No. 4, Pt. 2, Oct. 2001, p. 696A.*
Hayat et al., Effect of infliximab therapy for rheumatoid arthritis on chronic hepatitis C. Clinical Immunology vol. 103, No. 3, Pa 2, Supp., Jun. 2002, p. S80.*
Biancone et al., Immunomodulatory Drugs in Crohn's Disease Patients With Hepatitis B or C Virus Infection. Gastroenterology vol. 122, No. 2, Feb. 2002, pp. 593-594.*
The Merck Manual of Diagnosis and Therapy, Beers et al., Eds., Seventeenth Edition, published by Merck Research Laboratories, 1999, pp. 384-386.*
Campbell et al., Infliximab therapy for Crohn's disease in the presence of chronic hepatitis C infection. European Journal of Gastroenterology and Hepatology 13(2):191-192, 2001.
Abramson Steven
Amin Ashok
Browdy and Neimark , P.L.L.C.
Mosher Mary E.
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