Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – 3,10-dihydroxy-2-naphthacene carboxamide or derivative doai
Patent
1991-06-28
1993-07-20
Waddell, Frederick E.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
3,10-dihydroxy-2-naphthacene carboxamide or derivative doai
514926, 514927, A61K 3165
Patent
active
052293807
ABSTRACT:
The invention relates to a method of arresting and treating duodenal and gastric ulcers, and chronic gastritis comprising administering an effective amount of [4S(4.alpha.,4a.alpha.,5a.alpha.,12a.alpha.)]-4,7-bis (dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12, 2a-tetrahydroxy-1,11-dioxo-2-napthacenecarboxymide monohydrochloride.
REFERENCES:
Compendium of Drug Therapy, pp. 25:6-7, (1983-1984), Biomedical Information Corp., Publishers.
Chemical Abstracts, 112(5):135883(s), Magalhaes et al. (1989).
Warren, et al., "Unidentified Curved Bacilli on Gastric Epithelium in Active Chronic Gastritis," Lancet, vol. 1, 1983--pp. 1273-1275.
Marshall, et al., "Unidentified Curved Bacilli in the Stomach of Patients With Gastritis and Peptic Ulceration," Lancet, vol. 1, 1984--pp. 1311-1315.
Langenberg, et al., "The Pathogenic Role of Campylobacter Pyloris Studied by Attempts to Eliminate these Organisms," Abst. 98 in Proc. of the Third Int'l Workshop on Campylobacter Infections, Pearson, et al., eds., Public Health Laboratory Service, 1985--pp. 162-163.
Czinn and Speck, "Campylobacter pylori: A New Pathogen," J. Peds, vol. 144, 1989--pp. 670-672.
Henley III Raymond J.
Waddell Frederick E.
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