Method for treating headache pain with topical local anesthetic

Details Method for treating headache pain with topical local anesthetic Method for treating headache pain with topical local anesthetic

1995-10-30

1997-09-16

Kulkosky, Peter F.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Web, sheet or filament bases; compositions of bandages; or...

514817, A61L 1544, A61K 31135

Patent

active

056677995

ABSTRACT:
Methods are provided for the treatment of a host suffering from head ache pain with topical applications of a local anesthetic. The topical local anesthetic composition comprises an effective amount of a local anesthetic in combination with eucalyptol as a penetration enhancing agent, and optionally an additional penetration enhancing agent. The topical local anesthetic composition is applied to a keratinized skin site proximal to target nerves associated with the headache pain, usually to the supraorbital or occipital regions of the head. Upon application of the topical composition, the local anesthetic rapidly penetrates the skin to block conduction in the target nerves and provide pain relief to the host.

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Kittrelle et al., "Cluster Headache--Local Anesthetic Abortive Agents", Arch Neurol (1985), 42:496-498.

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