Method for treating glaucoma comprising administering to a...

Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,...

Reexamination Certificate

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C424S145100, C530S387100

Reexamination Certificate

active

07744873

ABSTRACT:
The present invention provides methods and kits for diagnosing and treating glaucoma.

REFERENCES:
patent: 5145871 (1992-09-01), Cavazza
patent: 5364884 (1994-11-01), Varma et al.
patent: 6207450 (2001-03-01), Sheffield et al.
patent: 6248571 (2001-06-01), Schmidt et al.
patent: 6248867 (2001-06-01), Nguyen et al.
patent: 6613563 (2003-09-01), Sosnowski et al.
patent: 9614411 (1996-05-01), None
patent: 9820889 (1998-05-01), None
patent: 0061774 (2000-10-01), None
patent: 0068247 (2000-11-01), None
patent: 0077021 (2000-12-01), None
patent: 02077006 (2002-10-01), None
patent: 02085909 (2002-10-01), None
Stabile et al., Blood, 109: 1834-1840, 2007.
Lappin et al., Nephrol. Dial. Transpl., 17 (Suppl): 65-67, 2002.
Agarwal et al., “Expression of Transforming Growth Factor Beta Isoforms (TGF-β 1-3) and Receptors (TGFβ RI-RIII) in Cultured Human Trabecular Meshwork Cells”, IOVS 38(4):S563 (1997).
Agarwal R, et al., “FAS-activated apoptosis and other apoptosis mediators in human trabecular meshwork cells,” Exp. Eye Res. 68:583-590 (1999.
Agarwal et al., “The Expression of Bone Morphogenetic Protein (BMP) and BMP Receptor mRNA by Human Trabecular Meshwork and Optic Nerve Head Cells and Tissues”, IOVS 41(4):S506 (2000).
Astrom, A.K., et al., “Chromosomal localization of three human genes encoding bone morphogenetic protein receptors”, Mammalian Genome 10(3):299-302 (1999).
Attisano L, Tuen Lee-Hoeflich S, “The Smads,” Genome Biol. 2(8) Reviews/3010.1 (2001) 1-8.
Bengtsson B, “Incidence of manifest glaucoma,” Br J Ophthalmol, 73:483-487 (1989).
Birren, et al., Genome Analysis, A Laboratory Manual vol. 2 Detecting Genes, (Bruce Birren ed., Cold Spring Harbor Laboratory Press 1998) 287-292.
Chang et al., “Haploinsufficient Bmp4 ocular phenotypes include anterior segment dysgenesis with elevated intraocular pressure”, BioMed Central, BMC Genetics, 2:18 (2001).
Chundru et al., “Detection of neurotrophins in human aqueous humor,” Invest. Ophthalmol. Vis. Sci. 41(4):S326 (2000).
Clark AF, et al., “Glucocorticoid-induced formation of cross-linked actin networks in cultured human trabecular meshwork cells,” Invest. Ophthalmol. & Vis. Sci. 35(1):281-294 (1994).
Clark AF, et al., “Cell biology of the human lamina cribrosa,” In Drance SM (ed). Optic Nerve in Glaucoma. Kugler Publications, New York: pp. 79-105 (1995).
Clark AF, et al., “Cytoskeletal changes in cultured human glaucoma trabecular meshwork cells,” J. Glaucoma 4:183-188 (1995).
Clark AF, et al., “Dexamethasone-induced ocular hypertension in perfusion-cultured human eyes,” Invest. Ophthalmol. & Vis. Sci. 36(2):478-489 (1995).
Clark AF, et al., “Inhibition of dexamethasone-induced cytoskeletal changes in cultured human trabecular meshwork cells by tetrahydrocortisol,” Invest. Ophthalmol. & Vis. Sci. 37(5):805-813 (1996).
Clark AF, et al., “Expression of the glaucoma gene myocilin (MYOC) in the human optic nerve head,” FASEB J. 15:1251-1253 (2001).
Clark AF, et al., “Glucocorticoid induction of the glaucoma gene MYOC in human and monkey trabecular meshwork cells and tissues,” Invest. Ophthalmol. & Vis. Sci. 42(8):1769-1780 (2001).
Cummings, Michael R., Human Heredity, Fourth Edition, (West/Wadsworth 1997) 266-283.
Dickerson JE, et al., “The effect of dexamethasone on integrin and laminin expression in cultured human trabecular meshwork cells,” Exp. Eye Res. 66:731-738 (1998).
Dudley et al., “A requirement for bone morphogenic protein-7 during development of the mammalian kidney and eye,” Genes & Development 9:2795-2807 (1995).
Elbashir SM, et al., “Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells”, Nature 411:494-498, 2001.
Encio et al., “The Genomic Structure of the Human Glucocorticoid Receptor”, J. Biol. Chem. 266(11):7182-7188 (1991).
Furuta and Hogan, “BMP4 is essential for lens induction in the mouse embryo,” Genes & Dev. 12:3764-3775 (1998).
Giguère et al., “Functional Domains of the Human Glucocorticoid Receptor”, Cell 46:645-652 (1986).
Greve, M. et al., “Comparison of the oculokinetic perimetry glaucoma screener with two types of visual filed analyser”, Can. J. Ophthamol. 28(5):201-206 (1993).
Grierson I et al., “Characteristics of Meshwork Cells and Age Changes in the Outflow System of the Eye: Their Relevance to Primary Open Angle Glaucoma.” In Mills KB (ed). Glaucoma. Proceedings of the Fourth International Symposium of the Northern Eye Institute, Manchester, UK, New York, Pergamon: pp. 12-31 (1988).
Gutteridge, “Normal tension glaucoma: diagnostic features and comparison with primary open angle glaucoma”; Clinical and Exp. Optometry; 83: 161-172 (2000).
Hernandez M and Gong H, “Extracellular matrix of the trabecular meshwork and optic nerve head.” in Ritch R., Shields, M.B., Krupin, T. (eds). The Glaucomas, 2nd ed. St Louis: Mosby-Year; pp. 213-249 (1996).
Hernandez, et al., “Changes in the Extracellular Matrix of the Human Optic Nerve Head in Primary Open-Angle Glaucoma,” Am. J. Ophthalmol. 109:180-188 (1990).
Hernandez MR and Pena JD, “The optic nerve head in glaucomatous optic neuropathy,” Arch Ophthalmol. 115:389-395 (1997).
Hitchings RA, “Glaucoma screening”, Br. J. Ophthamol. 77:326 (1993).
Jain, R.; “Vascular and interstitial barriers to delivery of therapeutic agents in tumors”; Cancer and Metastasis Reviews; 9; 253-266 (1990).
Liu X., et al.; Human trabecular meshwork cells express the ciliary neurotrophic factor (CNTF) tripartate receptor complex; Exp. Eye Res.; 72:711-717 (2001).
Hogan BL, “Bone morphogenic proteins: multifunctional regulators of vertebrate development,” Genes Dev. 10:1580-1594 (1996).
Hollenberg et al., “Primary Structure and Expression of a Functional Human Glucocorticoid Receptor cDNA”, Nature 318(19):635-641 (1985).
Hu and Ritch, “Hepatocyte Growth Factor is Increased in the Aqueous Humor of Glaucomatous Eyes,” J. Glaucoma 10:152-157 (2001).
Inatani et al., “Transforming growth factor β2 levels in aqueous humor of glaucomatous eyes,” Graefes Arch. Clin. Exp. Ophthalmol. 239:109-113 (2001).
Itoh et al., “Signaling of transforming growth factor-β family members through Smad proteins”, Eur. J. Biochem. 267:6954-6967 (2000).
Jacobson N, et al., “Non-secretion of mutant proteins of the glaucoma gene myocilin in cultured trabecular meshwork cells and in aqueous humor,” Human Molecular Genetics 10(2):117-125 (2001).
Jena et al., “BMP7 null mutation in mice: developmental defects in skeleton, kidney, and eye,” Exp. Cell Res. 230:28-37 (1997).
Jorde, et al., Medical Genetics, Second Edition, (Mosby 1999) 29-57.
Kawabata et al., “Signal Transduction by Bone Morphogenetic Proteins”, Cytokine & Growth Factor Reviews, vol. 9, No. 1, 49-61 (1998).
Kerrigan et al., “TUNEL-positive ganglion cells in human primary open-angle glaucoma,” Arch. Ophthalmol. 115:1031-1035 (1997).
Lambert et al., “Expression of TGF-Beta Isoforms and Their Receptor mRNA'S in Cultured Human Lamina Cribrosa Cells”, IOVS 38(4):S162 (1997).
Lambert, et al. “Map Kinase Activation and Cell Proliferation of Cultured Lamina Cribrosa Cells Following Exogenous NGF Treatment”, IOVS 41(4):S827 (2000).
Lambert W, et al., “Neurotrophin and neurotrophin receptor expression by cells from the human lamina cribrosa,” Invest. Ophthalmol. Vis. Sci., 42(10):2315-2323 (2001).
Leske MC, et al., “The Epidemiology of Open-Angle Glaucoma: A Review”, American Journal of Epidemilogy, 118 (2):166-191 (1983).
Liu et al., “Expression of Ciliary Neurotrophic Factor (CNTF), Glial Derive

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