Method for treating corneal endothelial wounds

Details Method for treating corneal endothelial wounds Method for treating corneal endothelial wounds

1992-07-23

1994-05-10

Moezie, F. T.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 23, 514912, 514961, 514970, 424 7804, A61K 3736

Patent

active

053107284

ABSTRACT:
A method for treating corneal endothelial wounds comprises administering TGF-.alpha. to the region of the wound in an amount sufficient to promote the healing of endothelial cells.
TGF-.alpha. advantageously is administered into the anterior chamber during ophthalmic surgical procedures, such as during intra-ocular lens implantation. The TGF-.alpha. preferably is administered as an active ingredient in an ophthalmological viscoelastic composition which improves the residence time of the growth factor in the anterior chamber.

REFERENCES:
patent: 4713446 (1987-12-01), DeVore et al.
patent: 4929442 (1990-05-01), Powell
patent: 4939135 (1990-07-01), Robertson
Pape, L. G. et al., Am. Intra-Ocular Implant Soc. J., vol. 6, p. 342 (1980).
DeLarco et al., Proc. Natl Acad. Sci., vol. 75:4001 (1978).
Marquardt et al., Science, 223:1079 (1984).
Schultz, G. S., et al. Science, 235:350 (1987).
Cifone et al., Proc. Natl Acad. Sci. USA 77:1039 (1980).
Haigler & Carpenter, Biochem. Biophys. Acta 598:314 (1980).
Rich et al., The Influence of Fibroblast Growth Factor on Healing of Cat Corneal Endothelium, ARVO 1989, Invest. Ophthal. Vis. Sci., 30(3).

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