Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2006-04-18
2006-04-18
Hui, San-Ming (Department: 1617)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C514S359000, C514S361000, C514S362000, C514S367000
Reexamination Certificate
active
07030119
ABSTRACT:
The invention features a method for treating chronic pain using a compound of formula (I).
REFERENCES:
patent: 5155110 (1992-10-01), Connor et al.
patent: 6469004 (2002-10-01), Barrett et al.
patent: WO 98/37881 (1998-09-01), None
patent: WO 00/35436 (2000-06-01), None
patent: WO 00/42022 (2000-07-01), None
Alessi, Dario R., et al., “PD 098059 Is a Specific Inhibitor of the Activation of Mitogen-activated Protein Kinase Kinase in Vitro and in Vivo”, J. Biol. Chem., 1995, pp 27489-27494, vol. 270, No. 46.
Hwang, Daniel, et al., “Expression of Mitogen-Inducible Cyclooxygenase Induced by Lipopolysaccharide: Mediation through both mitogen-activated protein kinase and NF-KB signaling pathways in macrophages”, Biochem Pharm, 1997, pp 87-96, vol. 54, Issue 1.
Larrivee, Jean-François, et al., “Role of the Mitogen-Activated Protein Kinases in the Expression of the Kinin B1 Receptors Induced by Tissue Injury ”, J Immunol, 1998, pp 1419-1426, vol. 160, No. 3.
Polakiewicz, Roberto D., et al., “A Mitogen-activated Protein Kinase Pathway Is Required for μ-Opioid Receptor Desensitization”, J. Biol. Chem., 1998, pp 12402-12406. vol. 273, No. 20.
PCT International Search Report PCT/US00/18345.
H. Bekemeier, et al., “Structure-Activity Relationship in Nonsteroidal Antinflammatory Agents, Including Qsar in Fenamate Derivatives”, Agents and Actions Supplements, Jul. 1, 1982, pp 17-34.
J. V. Duncia, et al., “MEK Inhibitors: The Chemistry and Biological Activity of U0126, Its Analogs, and Cyclization Products”, Bioorganic & Medicinal Chemistry Letters, 1998, pp 2839-2844, No. 8.
N. S. Duesbery, et al., “MEK Waars, a new front in the Battle Against Cancer”, Nature Medicine, Jul. 1999, pp 736-737, vol. 5, No. 7.
Ru-Rong Ji, et al., “Nociceptive-specific Activation of ERK in Spinal Neurons Contributes to Pain Hypersensitivity”, Nature Neuroscience, Dec. 1999, pp 1114-1119, vol. 2, No. 12.
Office Action for 10/031,149 (A0000104-01-SMH) dated May 11, 2005.
Barrett Stephen Douglas
Bridges Alexander James
Dixon Alistair
Lee Kevin
Pinnock Robert
Ashbrook Charles W.
Hui San-Ming
Pfizer Inc.
Purchase, Jr. Claude F.
Warner-Lambert & Company
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