Method for treating cardiac insufficiency with antibiotic A-2318

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...

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A61K 3142

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active

039858936

ABSTRACT:
A method for enhancing the contractile force of mammalian heart muscle which comprises administering an effective amount of antibiotic A-23187, a divalent cation ionophore.

REFERENCES:
J. Amer. Chem. Soc., 96, 1932 (1974), M. O. Cheney et al.
Ann. N.Y. Acad. Sci., 227, pp. 412-418, Feb. 1974.
S. W. Shaffer et al., Biochem. Pharmacol. 23, pp. 1609-1617, June 1974.

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