Method for treating cancer with water-insoluble s-camptothecin o

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Web – sheet or filament bases; compositions of bandages; or...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

514283, A61K 970, A61K 3144

Patent

active

055521541

ABSTRACT:
A method of treating specific forms of cancer with water-insoluble 20(S)-camptothecin compounds with the closed-lactone ring intact and/or derivatives thereof is disclosed. The method includes administering the compounds intramuscularly, orally and transdermally.

REFERENCES:
patent: Re32518 (1987-10-01), Miyasaka et al.
patent: 3894029 (1975-07-01), Winterfeldt et al.
patent: 4031098 (1977-06-01), Sugasawa
patent: 4357422 (1982-11-01), Giard et al.
patent: 4399276 (1983-08-01), Miyasaka et al.
patent: 4399282 (1983-08-01), Miyasaka et al.
patent: 4473692 (1984-09-01), Miyasaka et al.
patent: 4513138 (1985-04-01), Miyasaka et al.
patent: 4545880 (1985-10-01), Miyasaka et al.
patent: 4604463 (1986-08-01), Miyasaka et al.
patent: 4774236 (1988-09-01), Cook et al.
patent: 4867978 (1989-09-01), Gold
patent: 4874779 (1989-10-01), Senter
patent: 4894456 (1990-01-01), Wall et al.
patent: 4904768 (1990-02-01), Saulnier et al.
patent: 4914205 (1990-04-01), Sawada et al.
patent: 4939255 (1990-07-01), Tagawa et al.
patent: 4943579 (1990-07-01), Vishnuvajjala et al.
patent: 4981968 (1991-01-01), Wall et al.
patent: 5004758 (1991-04-01), Boehm et al.
patent: 5041424 (1991-08-01), Saulnier et al.
patent: 5049668 (1991-09-01), Wall et al.
patent: 5053512 (1991-10-01), Wani et al.
patent: 5061795 (1991-10-01), Tagawa et al.
patent: 5061800 (1991-10-01), Yaegashi et al.
patent: 5064823 (1991-11-01), Lee et al.
patent: 5106742 (1992-04-01), Wall et al.
patent: 5122526 (1992-06-01), Wall et al.
patent: 5122606 (1992-06-01), Wani et al.
patent: 5126351 (1992-06-01), Luzzio et al.
patent: 5145684 (1992-09-01), Liversidge et al.
patent: 5155225 (1992-10-01), Fortunak et al.
patent: 5162532 (1992-11-01), Comins et al.
patent: 5180722 (1993-01-01), Wall et al.
patent: 5225404 (1993-07-01), Giovanella et al.
Hsiang, Y.-H. et al., Cancer Res. 48: 1722-1726, 1988.
Wani, M. C. et al., J. Med. Chem. 30: 1774-1779, 1987.
Wani, M. C. et al., J. Med. Chem. 29: 2358-2363, 1986.
Hsiang, Y.-H. et al., J. Biol. Chem. 97: 14873-14878, 1985.
Hsiang, Y.-H. et al., Abstract 683 from The American Association for Cancer Research, vol. 29, Mar. 1988.
Wall, M. E. et al., J. Med. Chem. 29: 1553-1555, 1986.
Nelson, W. G. et al., Cancer Res. 47: 3246-3250, 1987.
Hsiang, Y.-H. et al., Cancer Res. 49: 4386-4389, 1989.
Wani, M. C. et al., J. Med. Chem. 30: 2317-2319, 1987.
Giovanella, B. C. et al., Cancer 52: 1146-1152, 1983.
Wani, M. C. et al., J. Med. Chem. 30: 1774-1779, 1987.
Wani, M. C. et al., J. Med. Chem. 23: 554-560, 1980.
Leibovitz, A. et al., Cancer Res. 36: 4562-4569, 1976.
Fogh, J. et al., in "Human Tumor Cells In Vitro," Fogh, Jr. ed., Plenum Press, New York, 1976, pp. 115-141.
Liu, L. F. et al., Proc. Nat'l. Acad. Sci. USA, 78: 3487-3491, 1981.
Muggla, F. M. et al., Cancer Chemo. Rep. 56: 515-521, 1972.
Gottlieb, J. A. et al., Cancer Chemo. Rep. 54: 461-470, 1970.
Jaxel, C. et al., Cancer Res. 49: 1465-1469, 1989.
Potmesil, M. et al., Cancer Res. 48: 3537-3543, 1988.
Chemical Abstracts, vol. 106(25), Abstract No. 207285z (1987).
Chemical Abstracts, vol. 106(15), Abstract No. 120133z (1987).
Chemical Abstracts, vol. 106(15). Abstract No. 11479a (1987).
Chemical Abstracts, vol. 106(13), Abstract No. 95753s (1987).
Chemical Abstracts, vol. 103(9), Abstract No. 64374c (1985).
Chemical Abstracts, vol. 101, Abstract No. 130677r (1984).
Chemical Abstracts, vol. 101(11), Abstract No. 91322z (1982).
Chemical Abstracts, vol. 101(10), Abstract No. 78770z (1984).
Chemical Abstracts, vol. 100(21), Abstract No. 167724j (1983).
Chemical Abstracts, vol. 100, Abstract No. 139434w (1984).
Chemical Abstracts, vol. 97, Abstract No. 188278b (1982).
Chemical Abstracts, vol. 96(9), Abstract No. 69271p (1981).
Chemical Abstracts, vol. 95(15), Abstract No. 133209h (1981).
Chemical Abstracts, vol. 94(12), Abstract No. 90169e (1980).
Chemical Abstracts, vol. 94(1), Abstract No. 4143n (1980).
Chemical Abstracts, vol. 92(5), Abstract No. 37766e (1980).
Chemical Abstracts, vol. 92(3), Abstract No. 18799b (1980).
Chemical Abstracts, vol. 90(4), Abstract No. 28930k (1979).
Chemical Abstracts, vol. 90(3), Abstract No. 22857v (1979).
Chemical Abstracts, vol. 84, Abstract No. 115629p (1976).
Xi-Ran et al., "Topical Camptothecine in Treatment of Psoriasis," Int'l. Journal of Dermatology, vol. 27, No. 7, pp. 475-476, Sep. 1988.
Ching-jung et al., "Effect of Topical Use of Camptothecine-Dimethyl Sulfoxide Solution in Psoriasis," Chinese Medical Journal, vol. 1, No. 5, pp. 355-360, Sep. 1975.
Tung et al., "Camptothecin Instillation and Local Injection for Prevention and Treatment of Urinary Bladder Tumors," Chinese Medical Journal, vol. 92, No. 1, pp. 57-60, 1979.
Pantazis et al., "Complete Inhibition of Growth Followed by Death of Human Malignant Melanoma Cells in Vitro and Regression of Human Melanoma Xenografts in Immunodeficient Mice Induced by Camptothecin," Cancer Research, vol. 52, No. 14, pp. 3980-3987, Jul. 15, 1992.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Method for treating cancer with water-insoluble s-camptothecin o does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method for treating cancer with water-insoluble s-camptothecin o, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for treating cancer with water-insoluble s-camptothecin o will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1948432

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.