Method for treating bacterial and protozoal infections

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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A61K 31505

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active

050029517

ABSTRACT:
A method for treating bacterial or protozoal humans and animals by administering a 6-aryl pyrimidine compound or a salt thereof in association with a pharmaceutical carrier.

REFERENCES:
patent: 2723977 (1955-11-01), Rorig
patent: 2776283 (1957-01-01), Rorig
patent: 2776285 (1955-03-01), Rorig
patent: 3956302 (1976-05-01), Hunter et al.
Nichols, Weed and Underwood, "Stimulation of Murine Interferon by a Substituted Pyrimidine", Antimicrobial Agents and Chemotherapy, vol. 9, No. 3, Mar. 1976, pp. 433-439.
Brown and Stevens, "Triazines and Related Products, Part XV, 2,4-Diaminopyrimidines and 2-Aminopyrimidin-4(3H)-Ones Bearing 1,2,3-Benzotriazinyl Groups as Potential Dihydrofolic Reductase Inhibitors", JCS Perkin I, pp. 1023-1028 (1975).
Shirakawa, Kenzo, "Pyrimidine Derivatives, IX, Mercapto-s-Triazolopyrimidines", Yakugaku Zasshi 80, pp. 1542-1550 (1960); cf CA 54, 24761h.
Kulkarni, K. D., Sabnis, S. S., and Kulkarni, B. S., "Chemotherapy of Bacterial Infections: Synthesis of Some Pyrimidine, Thiazole and Pyrazole Derivatives", J. Sci. and Ind. Res. Indil., vol. 19C, pp. 6-8, Jan. 1960.

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