Method for treating autoimmune disease using succinylacetone

Details Method for treating autoimmune disease using succinylacetone Method for treating autoimmune disease using succinylacetone

1988-05-06

1992-05-19

Robinson, Douglas W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Radical -xh acid, or anhydride, acid halide or salt thereof...

514885, A61K 3119

Patent

active

051149737

ABSTRACT:
The invention is a method of modulating or controlling autoimmune disease in a host. The method includes the step of administering to the diseased host a pharmaceutical effective amount of succinylacetone. The pharmaceutically effective amount of succinylacetone is desirably infused by an osmotic minipump in order to modulate the effects of autoimmune disease in the host.

REFERENCES:
patent: 4670467 (1987-06-01), Hess et al.
Paul, Fundamental Immunology, 1984, Raven Press, N.Y. pp. 312-313 and 777.
Stites et al, Basic and Clinical Immunology 1984 p. 274, 408 and 409, Lange Med. Pub.
Middleton et al., Allergy vol. 2, 1983 p. 1384-1385, C. V. Mosby Co.
Theodore et al, Clinical Allergy and Immunology of the Eye 1983 p. 106-108, Williams & Wilkins Press.
Nussenblat et al, Uveitis, 1989, pp. 38-46.
Bach et al, Immunology 1982 pp. 422-424 and 545-546.
Nussenblatt et al., Chem. Abst. 102(17):142909b (1985).
Tschudy et al., Chem. Abst. 96(25):210579d (1982).

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