Method for treating asthma

Drug – bio-affecting and body treating compositions – Effervescent or pressurized fluid containing – Organic pressurized fluid

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424 46, 514 56, 514826, A61K 912

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active

056909101

ABSTRACT:
A method of treating a patient suffering from antigen-induced asthma who has been challenged with an antigen, or providing chronic treatment to an asthma patient to reduce airway hyperresponsiveness, comprising intrabronchial administration to the patient of a pharmaceutical composition containing in each dose about 0.05 to about 1.0 mg of ultra-low molecular weight heparins (ULMWH), having an average molecular weight of 3,000 daltons or less, per kilogram of patient body weight, Inhalant pharmaceutical compositions for use in the novel treatment method are also provided.

REFERENCES:
Ahmed, et al., American Physiol. Soc., pp. 893-901 (1994).
Ahmed, Resp. Drug Delivery IV, pp. 55-63 (1994).
Ahmed, et al., American Physiol. Soc., pp. 1492-1498 (1993).
Ahmed, et al., N. Engl. J. Med., vol. 329, pp. 90-95 (1993).
Ahmed, et. al., Am. Rev. Respir. Dis., vol. 145, pp. 566-570 (1992).
Karnovsky et al., Airwaves and Vascular Remodelling, pp. 45-69 (1994).
Ashkin, et al., Am. Rev. Resp. Dis., vol. 147, No. 4, p. A660 (1993).
Lucio, et al., American Physiol. Soc., pp. 1093-1101 (1992).
Page, Lancet, vol. 337, pp. 717-720 (1991).

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