Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1987-12-02
1989-07-18
Schenkman, Leonard
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514947, A61K 31505
Patent
active
048494267
ABSTRACT:
A method for treating actinic keratosis comprising applying an effective amount of a cytotoxic drug dispersed in a pharmaceutically acceptable vehicle containing a penetrating solvent for the drug, the drug being applied to the skin area having the actinic keratosis growth without occlusion in pulses at an interval of once every from 3 to 30 days and preferably at an interval of from 4 to 14 days. Optimally, the penetrating solvent is free from toxic effects, such as propylene glycol, AZONE.RTM. or similar substituted azacycloalkyl-2-ones, tertiary amine oxides, and the like.
REFERENCES:
patent: 3989816 (1976-11-01), Rajadhyaksha
patent: 4423040 (1983-12-01), Rajadhyaksha
patent: 4636509 (1987-01-01), Phillips et al.
patent: 4705791 (1987-11-01), Benneche et al.
Remington's Pharmaceutical Sciences, 15th Ed., 1975, p. 1079.
Schenkman Leonard
Walker William B.
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