Surgery – Radioactive substance applied to body for therapy
Patent
1991-05-14
1994-03-22
Howell, Kyle L.
Surgery
Radioactive substance applied to body for therapy
128898, A61N 500
Patent
active
052959449
ABSTRACT:
A method is disclosed treating a tumor in a host by administering an ultrapurified polymerized hemoglobin solution to the host and thereafter administering ionizing radiation, such as X-rays, to the tumor. In a particularly preferred embodiment, the hemoglobin is bovine hemoglobin.
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patent: 4434788 (1984-03-01), Nakatsugawa
Teicher et al., Int. J. Radiation Oncol. 19:27 (1990).
Teicher et al., Int. J. Radiation Oncol. 21:969-974 (1991).
Song et al., Increase in pO.sub.2 and Radio sensitivity of Tumors by Fluosol-DA and Carbogen, Jan. 1987.
Reiss et al., Solubility and Transport Phenomena in Perfluorochemicals Relevant to Blood Substitution and Other Biomedica Applications, 1982.
Hopkins, 2nd Robert E.
Rausch Carl W.
Teicher Beverly A.
Biopure Corporation
Dana-Farber Cancer Institute
Howell Kyle L.
Lacyk John P.
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