Method for treating a picorna virus infection

Details Method for treating a picorna virus infection Method for treating a picorna virus infection

1975-06-10

1977-09-13

Goldberg, Jerome D.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Recombinant or stably-transformed bacterium encoding one or...

424263, 424285, 424300, A61K 3117, A61K 3144, A61K 3134, A61K 3127

Patent

active

040483339

ABSTRACT:
A method of treating picorna viral infections, particularly of the picornaviruses, is provided which comprises treating the patient with an effective amount of a compound of the formula ##STR1## wherein R is hydrogen or methyl; and R' is lower alkyl, allyl, .beta.-hydroxyethyl, .beta.-aminoethyl, .omega.-aminohexyl, a fatty acid radical, methoxyphenyl, chlorophenyl, phenyl, benzyl, tolyl, hydroxyphenyl, carboxyphenyl, chinoyl, carboxyhydroxyphenyl, hydroxynitrophenyl, nitrophenyl, hydroxychlorophenyl, chloronitrophenyl, phenylthioureidohexyl, trimethylphenyl, methylchlorophenyl, pyridyl, acetylphenyl, acetylaminophenyl, dimethylaminophenyl, aminopyridyl, phenylthioureidopyridyl, phenylthioureidonaphtyl, aminonaphthyl, chlorophenylthioureidophenyl, furfuryl, dichlorophenyl or allylthioureidophenyl. The compound may be administered orally, preferably in dosages of from 40 to 200 mg per kilogram body weight.

REFERENCES:
chemical Abstracts 77: 29549m, July 31, 1972.

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