Method for treating a mammal suffering from a T-cell medicated d

Details Method for treating a mammal suffering from a T-cell medicated d Method for treating a mammal suffering from a T-cell medicated d

1994-11-03

1996-08-13

Parr, Margaret

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

Structurally-modified antibody, immunoglobulin, or fragment...

4241301, 4241431, 4241731, 4241741, 435 703, 435 711, 4352401, 4353201, 5303871, 53038822, 53038873, 53038875, 5303888, 5303891, 5303896, 5303897, A61K 3516, A61K 3900, A61K 39395, C04K 1600

Patent

active

055454046

ABSTRACT:
The invention relates to a CHO cell-line capable of producing antibody, the cell-line having been co-transfected with a vector capable of expressing the light chain of the antibody and a vector capable of expressing the heavy chain of the antibody wherein the vectors contain independently selectable markers; also included is a CHO cell-line capable of producing a human antibody or an altered antibody, the cell-line having been transfected with a vector capable of expressing the light chain of the antibody and the heavy chain of the antibody; process for the production of antibody using a CHO cell-line and antibody having CHO glycosylation.

REFERENCES:
patent: 4816567 (1989-03-01), Cabilly et al.
patent: 5089397 (1992-02-01), Kushner et al.
Kaufman et al., Mol. Cel Biol., 5:1750-1759 (1985).
Zettlmeissl et al., Bio/Technology, 9:720-725 (1987).
Page, M. J. et al., Bio/Technology, 9 (Jan. 1991).
Goochee and Monica, Biotechnology 8 (1990), pp. 421-427.
Leatherbarrow et al., Molecular Immunology 22 (1985), pp. 407-415.
Nose and Wigzell, Proc. Nat. Acad. Sci 80 (1983), pp. 6632-6636.
Weidle, U. H. , et al., Gene, 51:21-29 (1987).
Feys, V. et al., Int. J. Cancer: Supplement 2:26-27 (1988).
Weidle et al., Gene, 60:205-216 (1987).
Nakatani et al., Bio/Technology, 7:805-810 (1989).
Gillies et al., Bio/Technology, 7:799-804 (1989).
Waldmann [Science 252:1657-1662 (1991)].
Harris et al., [TIBTECH 11:42-44 (1993)].
Osband et al., [Immunotherapy 11(6): 193-195 (1990)].
Dillman[Ann. Internal Med. 111:592-600(1989) ].
Hird et al. [Genes and Cancer (1990) chapter 17].
Curti [Critical Reviews in Onocology/Hematology 14:29-39 (1993)].
Benjamin et al. [Nature 320:449-451 (1986)].
Riechmann et al. [Nature 332:323-327 (1988)].
Borrebaeck et al. Immunology Today 14(10):477-479 (1993).
Galili Immunology Today 14(10):480-482 (1993).
Emmery et al. Exp. Opin. Invest. Drugs 3(3):241-251 (1994).
Rademacher et al. Ann. Rev. Biochem. 57:785-838 (1988).
Hale Progress Report-MRC Wellcome Therapeutic ANtibody Centre (1990).
Hale et al. Lancet 394-399 (Dec. 17, 1988).
Lim et al. Lancet 341:432-433 (1993).
Lockwood et al. Lancet 341:1620-1622 (1993).
Poynton et al. Lancet 341:1037 (1993).
Hale Progress Report-MRC Wellcome Therapeutic ANtibody Centre (1990).

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