Method for transporting substances into living cells and tissues

Chemistry: molecular biology and microbiology – Treatment of micro-organisms or enzymes with electrical or... – Modification of viruses

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

4351723, 435173, 935 52, 935 53, 935 57, C12N 1587

Patent

active

051007924

ABSTRACT:
Inert or biologically active particles are propelled at cell at a speed whereby the particles penetrate the surface of the cells and become incorporated into the interior of the cells. The process can be used to mark cells or tissue or to biochemically affect tissues or tissue in situ as well as single cells in vitro. Apparatus for propelling the particles toward target cells or tissues are also disclosed. A method for releasing particles adhered to a rotor device is also disclosed.

REFERENCES:
patent: 2761734 (1956-09-01), Farmer
patent: 3207445 (1965-09-01), Court et al.
patent: 3515130 (1970-06-01), Tsujino
patent: 3853125 (1974-12-01), Clark et al.
patent: 4124024 (1978-11-01), Schwebel et al.
patent: 4446990 (1984-05-01), Stevenson et al.
patent: 4473328 (1984-09-01), Hengesbach
patent: 4527884 (1985-07-01), Nusser
The Washington Post, May 18, 1987, p. A12.
Bankert et al., Transcription Proceeding, vol. 12, No. 3 (1980), pp. 443-446.
Browne, "Shotgun's Blast May Create New Forms of Life", The New York Times, May 26, 1987.
Klein et al., Nature, vol. 327, No. 6117, May 7, 1987, pp. 70-73.
Perry et al. (edit.), Chemical Engineer's Handbook, McGraw-Hill, New York (1973), pp. 6-5 through 6-7.
Sanford et al., "Delivery of Substances into Cells and Tissues Using a Particle Bombardment Process", Particulate Science and Tech., vol. 5 (1987), pp. 27-37.
Klein, T. M., E. C. Harper, Z. Svab, J. C. Sanford, M. E. Fromm, P. Maliga, 1988, Stable genetic transformation of . . . by the particle . . . PNAS 85:8502-8505.
Sanford, J., 1988, The biolistic process-a new concept . . . Trends in Biotechnology, 5:299-302.
Klein, T. M., M. E. Fromm, A. Weissinger, D. Tomes, S. Scjhaaf, M. Sleeten, and J. C. Sanford, 1988 . . . Proc. Natl. Acad. Sci. 85:4305-4309.
Klein, T. M., T. Gradziel, M. E. Fromm, and J. C. Sanford, 1988, Factors influencing gene delivery into Zea mays cells . . . microprojectiles, Biotechnology, 6:559-563.
Boynton, J. E., N. W. Gillham, E. H. Harris, J. P. Hosler, A. M. Johnson, A. R. Jones, . . . 1988, Chloroplast transformation of . . . microprojectiles, Science 240:1534-1538.
Johnston, S. A., R. Butow, K. Shark, and J. C. Sanford, 1988, Transformation of yeast . . . microprojectiles, Science 240:1558-1541.
McCabe, D. E., B. J. Martinell, and P. Christou, 1988, Stable transformation of soybean (Glycine max) plants, Bio/Technology 87:923-926.
Christou, P., D. E. McCabe, and W. F. Swain, 1988, Stable transformation of soybean callus by DNA-coated gold particles, Plant Physiology 87:671-674.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Method for transporting substances into living cells and tissues does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method for transporting substances into living cells and tissues, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for transporting substances into living cells and tissues will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-2258488

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.