Method for transformation of anaerobic microorganisms

Chemistry: molecular biology and microbiology – Vector – per se

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435 68, 4351723, 435842, 935 29, 935 56, C12N 1500, C12N 100, C12P 2100, C12R 1145

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046908978

ABSTRACT:
Method for transforming anaerobic microorganisms. Anaerobic microorganisms are induced to form L-forms. Genetic material capable of inducing the desired phenotype is introduced into the L-forms, after which the L-forms may be caused to regenerate their cell wall. These methods are also useful for obtaining desired biological products. Additionally, shuttle vectors capable of transforming both aerobic and anaerobic microorganisms are set forth.

REFERENCES:
patent: 4332900 (1982-06-01), Manis et al.
patent: 4477576 (1984-10-01), Chang et al.
patent: 4493893 (1985-01-01), Mielenz et al.
Allcock et al, App and Env Micro, vol. 43(3) pp. 719-721, Mar. 1982, "Clostricium Acetobutylicum Protoplast Formation and Regeneration".
Rood et al, Plasmid, vol. 1, pp. 563-570, 1978, "Identification of a Transferable Tretracycline Resistance Plasmid CW3 from Clostridium Perfringens".
Madoff, Subrelle The Prokcyotes, Springer-Verlag, vol. VII pp. 2225-2236, 1981.

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