Chemistry: analytical and immunological testing – Biological cellular material tested
Patent
1983-01-03
1984-11-27
Turk, Arnold
Chemistry: analytical and immunological testing
Biological cellular material tested
436 10, 436 17, G01N 3348, G01N 3372
Patent
active
044851758
ABSTRACT:
A method and reagent system is described for differential determination of three-populations of leukocytes (lymphocyte, monocyte and granulocyte), using an automatic counting system. The reagent system includes a blood diluent and lysing reagent. The blood diluent is an osmotically balanced aqueous solution of ingredients at a preselected pH for maintaining erythrocyte morphology, blood cell stabilizing, buffering and bacteriostatic action. The lysing reagent is a mixture of an aqueous solution of quaternary ammonium salts, which lysing reagent is added to the diluted blood under more mild conditions of concentration and at a slower rate than is current practice in order to obtain an unexpected volumetric modification of at least one of the three-populations of leukocytes, whereby volumetric differential analysis can be accomplished.
REFERENCES:
patent: 3874852 (1975-04-01), Hamill
patent: 4213876 (1980-07-01), Crews et al.
patent: 4286963 (1983-09-01), Ledis et al.
patent: 4346018 (1982-08-01), Carter et al.
Nicol, D. J. et al., J. Clinical Pathology, (1971), 24, p. 882.
Davis, R. E. et al., J. Med. Lab. Techol. (1969), 26, 26-29.
Barnard, D. F. et al., J. Clin. Path., 22, Suppl. Coll. Path, (1969), 3, 26-33.
Ballard, B. C. D., J. Clin. Path., 25, p. 460, (1972).
Hatch et al., Am. J. Clin. Path., 36, 220-223, (1961).
Armak Arquad, 81-6, Bulletin.
J. M. England et al., Lancet, Mar. 1, 1975, p. 492.
J. M. England et al., Lancet, May 22, 1976, p. 1143.
J. M. England et al., J. Clin. Path., 27, 623, (1974).
P. A. Wycherly and M. J. O'Shea, J. Clin. Path., 31, p. 271, (1978).
D'Angelo et al., J. Clin. Path., 38, No. 6, 658-662.
Carter, II James H.
Crews Harold R.
Ledis Stephen L.
Sena Ted
Coulter Electronics Inc.
Hibnick Gerald R.
Sparks Meredith P.
Turk Arnold
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