Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2005-01-21
2009-12-08
Nguyen, Bao-Thuy L (Department: 1641)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S004000, C435S005000, C435S287100, C435S287700, C435S970000, C435S975000, C435S007910, C436S514000, C436S518000, C436S507000, C436S530000, C436S807000, C436S821000, C436S810000, C422S051000, C422S051000, C422S051000, C422S067000, C422S067000
Reexamination Certificate
active
07629127
ABSTRACT:
This disclosure teaches a method and composition for detecting the presence of class specific antibodies reactive with analytes such as bacteria, allergens, autoimmune antigens, viral proteins, haptens, and carbohydrates by lateral flow techniques. In one embodiment of the disclosure, a test sample is added to the test strip, which then migrates to the site of the immobilized allergens, thereby forming a first antibody IgE-allergen complex. A chase release buffer is added upstream to or from the site of the labeled anti-IgE antibodies, which is itself upstream from the sample site. The anti-IgE antibodies migrate downstream to the site of immobilized first complex, thereby forming a second complex indicating the presence of class specific IgE antibodies in the test specimen. In another embodiment of the disclosure, a liquid form of the labeled anti-IgE antibodies can be added to the test strip after the first complex has been formed.
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Dexall Biomedical Labs, Inc.
Grant Jonathan E.
Grant Patent Services
Nguyen Bao-Thuy L
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