Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Separation or purification
Patent
1995-06-07
1998-07-21
Huff, Sheela
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Separation or purification
530810, 436523, 436524, 436525, 436531, 436824, 435 71, C07K 100, C07K 1400, C07K 1600, C07K 1700
Patent
active
057836744
ABSTRACT:
A method for the separation of at least one specific binding entity from a mixture of binding entities by the steps of contacting a mixture of binding entities with immobilized peptides in which the peptides specifically bind to the specific binding entities and the peptides contain an amino acid which facilitates removal of the binding entities from the peptides, and separating the immobilized peptide/specific binding entity complexes from the mixture of binding entities. A change in incubation conditions facilitates removal of the binding entities from the immobilized peptides.
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Schoofs et al. J. Immunol. vol. 140 p. 611, Jan. 1988.
Blackburn Robert P.
Chiron Corporation
Goldman Kenneth M.
Huff Sheela
Nakamura Dean H.
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