Method for the treatment of withdrawal symptoms associated with

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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424 81, 424449, 424485, 424486, 514813, 514936, 514944, 514946, A61K 3144, A61K 3178, A61F 1302

Patent

active

049468537

ABSTRACT:
A preparation for the once-daily, percutaneous administration of nicotine comprises nicotine uniformly distributed in a solid, semi-solid or mucilaginous medium which can be placed in intimate contact with the skin, the solid, semi-solid or mucilaginous medium is formed by adding a given amount of nicotine to a solution of a solidifying or gel-forming agent or mixture thereon in a suitable solvent or mixture of solvents and mixing or heating the mixture thereby obtained so as to form the solid, semi-solid or mucilaginous medium.
The preparation can be used in a method of treating withdrawal symptoms associated with smoking cessation and for combating the psychological dependence that occurs through frequency smoking.

REFERENCES:
patent: 4597961 (1986-07-01), Etscorn
patent: 4675009 (1987-06-01), Hymes et al.
patent: 4680172 (1987-07-01), Leeson
Rose et al., Drug and Alcohol Dependence, 13, 209-213 (1984).
Rose et al., Clin. Pharmacol. Ther., vol. 38, No. 4 (Oct., 1985).

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