Method for the treatment of skin disorders using inhibitor of ch

Details Method for the treatment of skin disorders using inhibitor of ch Method for the treatment of skin disorders using inhibitor of ch

1997-10-15

2000-10-03

Venkat, Jyothsan

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Cosmetic, antiperspirant, dentifrice

514460, 514864, 514880, 514859, 514944, 514969, A61K 748

Patent

active

061269476

ABSTRACT:
An inhibitor of cholesterol synthesis is used for the treatment, alleviation or prevention of skin disorders.

REFERENCES:
patent: 4231938 (1980-11-01), Monaghan et al.
patent: 5730992 (1998-03-01), Sanion et al.
*J.S. Strauss, "Pathogenesis of Acne: How Might Azelaic Acid Act?", Journal of Dermatological Treatment (1989) I, 3-6.
*H. Gollnick, "The New Therapeutic Agent: Azelaic Acid in Acne Treatment", Journal of Dermatological Treatment (1990) 1 (Suppl 3): S23-S28.
*Goldstein, Joseph L. and Brown, Michael S., "Regulation of the Mevalonate Pathway", Nature, vol. 343, Feb. 1, 1990, 425-430.
*The Merck Index, An Encyclopedia of Chemicals, Drugs and Biologicals, 11th Edition, 1989.
Negre-Aminou, Pascale et al., Biochimica et Biophysica Acta 1345 (1997) 259-268.
Amin, Dilip et al., The Journal of Pharmacology and Experimental Therapeutics, vol. 281, No. 2, 1997, 746-752.
Eisele, Bernhard et al., Journal of Lipid Research, vol. 38, 1997, 564-575.

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