Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1989-02-13
1991-02-19
Lee, Lester L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
530322, A61K 3702
Patent
active
049944401
ABSTRACT:
The present invention relates to a method for the treatment of renal cell carcinoma comprising administering to a warm blooded mammal in need thereof a therapeutically effective amount of N-acetylmuramyl-L-alanyl-D-isogutamin-yl-L-alanine-2-(1,2-dipalmitoyl-sn-g lyc ro-3-hydroxyphosphoryloxy)ethylamide monosodium salt preferably encapsulated in a multilamellar liposomal composition comprising phosphatidylcholine and phosphatidylserine.
REFERENCES:
patent: 4548923 (1985-10-01), Hartmann et al.
patent: 4619794 (1986-10-01), Hanser
patent: 4738843 (1988-04-01), Oguchi et al.
patent: 4774085 (1988-09-01), Fidler
Creaven et al., Liposomes in the Therapy of Infectious Diseases and Cancer, pp. 297-303 (1989).
Comprehensive Textbook of Oncology, pp. 889-900, Williams and Wilkins, Baltimore (1986).
J. Of Urology, 117, pp. 272-275 (1977).
Cancer Principles & Practice of Oncology, 3rd Ed., (1989), p. 991.
Fishman Irving M.
Lee Lester L.
Villamizar JoAnn
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