Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...
Patent
1993-01-26
1994-05-31
Waddell, Frederick E.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Nitrogen containing other than solely as a nitrogen in an...
A61K 31155
Patent
active
053170407
ABSTRACT:
A method for the treatment of pertussis is disclosed which comprises administering a selective inhibitor of inducible nitric oxide synthase, preferably aminoguanidine, to a mammalian host susceptible to pertussis in a small but effective amount for inhibiting the toxic effects of TCT released by Bordetella pertussis.
REFERENCES:
patent: 4704274 (1987-11-01), Sakuma et al.
patent: 5077313 (1991-12-01), Lubec
patent: 5128360 (1992-07-01), Cerami et al.
patent: 5132453 (1992-07-01), Griffith
patent: 5158883 (1992-10-01), Griffith
patent: 5196450 (1993-03-01), Sjoerdsma et al.
Goldman et al., Infect. Immun. 36, 782-794 (1982).
Cookson et al., Infect. Immun. 57, 2223-2229 (1989).
Cookson et al., Biochemistry 28, 1744-1749 (1989).
Corbett et al., Diabetes 41, 552-556 (1992).
Goldman and Baseman, In Vitro 16, 313-319 (1980).
Green et al., Anal. Biochem. 126, 131-138 (1982).
The Merck Manual, Fourteenth Edition, pp. 1897-1899 (1982).
Criares T. J.
Meyer Scott J.
Waddell Frederick E.
Washington University
LandOfFree
Method for the treatment of pertussis with aminoguanidine does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method for the treatment of pertussis with aminoguanidine, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for the treatment of pertussis with aminoguanidine will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1628436