Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert
Patent
1991-05-28
1994-11-22
Kishore, G. S.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Implant or insert
264 43, 264 46, 424423, 424435, 424486, 424489, 42721332, 42721336, 514900, 514963, 514951, A61K 600, A61K 952
Patent
active
053667336
ABSTRACT:
Oral compositions for the local administration of a therapeutic agent to a periodontal pocket of a patient for alleviating dental disease comprise a plurality of dry, discrete microparticles each of which comprise an effective amount of at least one therapeutic agent dispersed in a matrix comprising a biocompatible and biodegradable polymer. Apparatus and methods are also provided for the dispensing of the dry microparticles to the periodontal pocket whereby they become tacky and adhere to the involved tissue so as to induce long term therapeutic benefits.
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Brizzolara Nancy S.
Lanzilotti Michael G.
Lawter James R.
American Cyanamid Company
Costigan James V.
Jackson H. G.
Kishore G. S.
Spear James M.
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