Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1991-12-13
1992-11-24
Waddell, Frederick E.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514219, A01N 4362
Patent
active
051662027
ABSTRACT:
Midazolam and its pharmaceutically acceptable salts are useful in the treatment of panic disorder, panic attacks and the prevention of panic attacks.
REFERENCES:
patent: 4950664 (1990-08-01), Goldberg
Ballenger, J. C. et al., "Alprazolam in panic disorder and agoraphobia: results from a multicenter trial. I. Efficacy in short-term treatment," Arch Gen Psychiatry, 45:413-422 (1988).
Wheeler, E. O., et al., "Neurocirculatory asthenia: a 20-year follow-up study of 173 patients," JAMA, 142:878-889 (1950).
Breier A. et al., "Agoraphobia with panic attacks: development, diagnostic stability, and course of illness," Arch Gen. Psychiatry, 43:1029-1036 (1986).
Noyes, R. et al., "Problems with tricyclic antidepressant use in patients with panic disorder or agoraphobia: results of a naturalistic follow-up study," J. Clin. Psychiatry, 50163-169 (1989).
Nagy, L. M. et al., "Clinical and medication outcome after short-term alprazolam and behavioral group treatment in panic disorder," Arch Gen Psychiatry, 46:993-999 (1989).
Noyes, R. et al., "Follow-up study of patients with panic disorder and agoraphobia with panic attacks treated with tricyclic antidepressants," J. Affective Disord, 16:249-257 (1989).
Mavissakalian, M. et al., "Imipramine in the treatment of agoraphobia: dose-response relationships," Am J. Psychiatry, 142:1032-1036 (1985).
Rickels, K. et al., "Chronic therapeutic use of benzodiazepines: I. Effects of abrupt discontinuation," Arch Gen Psychiatry (in press).
Schweizer, E. et al., "Chronic therapeutic use of benzodiazepines: II. Effects of gradual taper," Arch Gen. Psychiatry (in press).
Roy-Byrne, P. P. et al., "Benzodiazepine withdrawal: overview and implications for the treatment of anxiety." Am J. Med., 84:1041-1052 (1988).
Reves, J. G. et al., "Midazolam" pharmacology and uses, Anesthesiology, 62:310-324 (1985).
Dundee, J. W. et al., "Midazolam" a review of its pharmacological properties and therapeutic use, Drugs, 28:519-541 (1984).
Forrest, P. et al., "Placebo controlled comparison of midazolam, triazolam and diazepam as oral premedicants for outpatient anaesthesia," Anaesth Intens Care, 15:296-304 (1987).
O'Boyle, C. A. et al., "Comparison of midazolam by mouth and diazepam IV in outpatient oral surgery," Br J. Anaesth, 59:746-754 (1987).
Hargreaves, J., "Benzodiazepine premedication in minor day-case surgery: comparison of oral midazolam and temazepam with placebo," Br J. Anaesth, 61:611-616 (1988).
Clausen, T. G., et al., "Pharmacokinetics of midazolam and alpha-hydroxy-midazolam following rectal and intravenous administration," Br J. Clin. Pharmacol, 25:457-463 (1988).
Wilton, N. C. T. et al., "Preanesthetic sedation of preschool children using intranasal midazolam," Anesthesiology, 69:972-975 (1988).
Noyes, R. et al., "Alprazolam in panic disorder and agoraphobia: Results from a multicenter trial. II. Patient acceptance, side effects, and safety," Arch Gen Psychiatry, 45:423-428 (1988).
Greenblatt, D. J. et al., "Pharmacokinetic and electroencephalographic study of intravenous diazepam, midazolam, and placebo," Clin. Pharmacol Ther, 45:356-365 (1989).
Sostmann, H. J. et al., "Dose equivalence of midazolam and triazolam," Eur J. Clin Pharmacol, 36:181-187 (1989).
Forster A., "Respiratory depressant effects of different doses of midazolam and lack of reversal with naloxone-a double-blind randomized study", Anesth Analg, 62:920-924 (1983).
Curtis, L. D. et al., "Arterial oxygen desaturation following intravenous injection of midazolam," J Amer Assoc of Nurse Anesth, 57:244-249 (1989).
Rickels, K. et al., "Long-term diazepam therapy and clinical outcome," JAMA, 250:767-771 (1983).
Rickels, K. et al., "Long-term treatment of anxiety and risk of withdrawal. Prospective comparison of clorazepate and buspirone," Arch Gen Psychiatry, 45:444-450 (1988).
Allen, R. P. et al., "Efficacy without tolerance or rebound insomnia for midazolam and temazepam after use for one to three months," J Clin Pharmacol, 25:457-463 (1987).
Koopmans, R. et al., "Pharmacokinetic-pharmacodynamic modeling of midazolam effects on the human central nervous system," Clin Pharmacol Ther, 44:14-22 (1988).
Schweizer, E. et al., "Lorazepam vs. alprazolam in the treatment of panic disorder," Pharmacopsychiatry, 23:90-93 (1990).
de Wit, H. et al., "Lack of preference for diazepam in anxious volunteers," Arch Gen Psychiatry, 43:533-541 (1986).
Ciraulo, D. A. et al., "Parental alcoholism as a risk factor in benzodiazepine abuse: a pilot study," Am J Psychiatry, 146:1333-1335 (1989).
Criares T. J.
Trustees of the University of Pennsylvania
Waddell Frederick E.
LandOfFree
Method for the treatment of panic disorder does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method for the treatment of panic disorder, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for the treatment of panic disorder will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-922035