Method for the treatment of organ ischemia or infarct comprising

Chemical apparatus and process disinfecting – deodorizing – preser – Blood treating device for transfusible blood

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604 4, 604 6, A61M 114, A61M 3700

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active

060077743

ABSTRACT:
A method for treating conditions associated with ischemia or infarct is disclosed which includes the steps of administering a biocompatible non-blood oxygen carrier while monitoring one or more oxygenation indices to maintain oxygenation of the patient's tissues at or above a predetermined level.

REFERENCES:
patent: 3975512 (1976-08-01), Long, Jr.
patent: 4073879 (1978-02-01), Long, Jr.
patent: 4301144 (1981-11-01), Iwashita et al.
patent: 4473494 (1984-09-01), Tye
patent: 4526715 (1985-07-01), Kothe et al.
patent: 4600531 (1986-07-01), Walder
patent: 4698387 (1987-10-01), Schmidt et al.
patent: 4777244 (1988-10-01), Bonhard et al.
patent: 4857636 (1989-08-01), Hsis
patent: 4861867 (1989-08-01), Esep
patent: 4911929 (1990-03-01), Farmer et al.
patent: 4987154 (1991-01-01), Long, Jr.
patent: 5344393 (1994-09-01), Roth et al.
patent: 5451205 (1995-09-01), Roth et al.
George P. Biro, et al., The Effect of Hemodilution with Fluorocarbon or Dextran on Regional Myocardial Flow and Function During Acute Coronary Stenosis in the Pig, 1 The Am. J. of Cardiovascular Pathology 99, (1987).
B. vonBormann, Blutsparende Verfahren--anasthesiologische Aspekte p. 194 (15, 1989) (Abstract in English).
135 James D. Colt, The Use of Stroma-Free Hemoglobin Solution for Partial Exchange Transfusion in Aortic Resection in Dogs, 135 The Am. J. of Surgeory, 656 (1978).
30 Kazuaki Fukushima et al., Clinical Experience of Autologous Blood Transfusion by Hemodilution with Fluosol-DA, Jpn. J. Anesthesiol, 741 (1981).
R. Bruce Light et al., Perfluorochemical Artificial Blood as a Volume Expander in Hypoxemic Respiratory Failure in Dogs, Chest, 444 (1987).
13 Charles L. Rice et al., Blood and Blood Substitutes: Current Practice, Advances in Surgeory, 93 (1979).
20 Jean G. Riess, Overview of Progress in the Fluorocarbon Approach to in vivo Oxygen Deliver, Biomater, Artif. Cells Immobilization Biotechnol., 183 (1992).
100 Gus J. Vlahakes, Hemodynamic effects of oxygen transport properties of a new blood substitute in a model of massive blood replacement, J. Thorac. Cardiovasc. Surg., 379 (1990).
Faithfull, et al. "Peripheral Vascular Responses to Fluorocarbon Administration" Microvascular Research 33:183-193 (1987).
Faithfull, et al. "Critical Levels of O.sub.2 Extraction Following Hemodilution with Dextran or Fluosol-DA" J. of Critical Care 3(1): 14-18 (1988).
Federspiel, et al. "A Theoretical Analysis of the Effect of the Particulate Nature of Blood on Oxygen Release in Capillaries" Microvascular Research 32: 164-189 (1986).
Gutierrez, G. "The Rate of Oxygen Release and Its Effects on Capillary O.sub.2 Tension: A Mathematical Analysis" Respiration Physiology 63: 79-96 (1986).
Homer, et al. Oxygen Gradients Between Red Blood Cells in the Microcirculation: Microvascular Research 22: 308-323 (1981).
Mebmer, et al. "Oxygen Supply to the Tissues During Limited Normovolemic Hemodilution" Res. Exp. Med. 159: 152-166 (1973).
Mercuriali, et al. Autologous Blood, pp. 2-30 Transmedica Europe Limited, Eastbourne, United Kingdom (1991).
Messmer, et al. "Present State of Intentional Hemodilution " Eur. Surg. Res. 18: 254-263 (1986).
NIH Consensus Conference "Perioperative Red Blood Cell Transfusion" JAMA 260(18): 2700-2703 (1988).
Riess, et al. "Reassessment of Criteria for the Selection of Perfluorochemicals for Second-Generation Blood Substitutes: Analysis of Structure/Property Relationships" Artificial Organs 8(1): 44-56 (1984).
Riess, et al. "Design, Synthesis and Evaluation of Fluorocarbons and Surfactants For In Vivo Applications: New Perfluoroalkylated Polyhydroxylated Surfactants" Int'l Symposium on Blood Substitutes, Montreal, (May, 1987) pp. 421-430.
Gould, et al. "Fluosol-DA As A Red-Cell Substitute in Acute Anemia" New England Journal of Medicine 314(26): 1653-1656 (1986).
Stehling, et al. "Acute Normovolemic Hemodilution" Transfusion 31(9): 857-868 (1991).
Weiskoff, R.B. "Mathematical Analysis of Isovolemic Hemodilution Indicates that It Can Decrease the Need for Allogeneic Blood Transfusion" Transfusion 35(1): 37-41 (1995).
Winslow, R. "A Model for Red Cell O.sub.2 Uptake" International J. of Clinical Monitoring and Computing 2: 81-93 (1985).
Zauder, H. "Preoperative Hemoglobin Requirements" Anesthesiology Clinics of North America 8(3): 471-480 (1990).

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