Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1997-05-12
1999-05-11
Jarvis, William R. A.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514258, A61K31/55;31/505
Patent
active
059028076
ABSTRACT:
The invention relates to a method for treating a mammal suffering from mental illness induced by propagation of stress, said method comprising the step of removing or diminishing the tone of the endogenous alpha-2C-adrenoceptors in the central nervous system of said mammal. The invention relates further to pharmaceutical compositions useful for said treatment.
REFERENCES:
Angst, J. et al., "Double blind study with HF 1854 (8-chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo diazepine) in comparison with levomepromazine", Pharmakopsychiat./Neuro-Psychopharmakol. 4(4), 1971, pp. 192-200, an abstract from Caplus, An 1972:196.
Angst, J. et al., "Ergebnisse eines Doppelblindversuches von HF 1854* (8-Chlor-11-(4-methyl-1-piperazinyl)-5H-dibenzo (b, e) (1,4) diazepin) im Vergleich zu Levomepromazin", Pharmakopsychiat./Neuro-Psychopharmakol. vol. 4, 1971, pp. 192-200, Georg Thieme Verlag, Stuttgart.
Spivak, B. et al., "Reduction of Aggressiveness and Impulsiveness during Clozapine Treatment in Chronic Neuroleptic-Resistant Schizophrenic Patients", Clinical Neuropharmacology 20(5), 1997, pp. 442-446.
Sallinen, J. et al., "Adrenergic .alpha..sub.2C -Receptors Modulate the Acoustic Startle Reflex, Prepulse Inhibition, and Aggression in Mice", Journal of Neuroscience 18(8), 1998, pp. 3035-3042.
Lott et al, Chemical Abstracts, vol. 126, abstract no. 84506, 1996.
Inoue et al, Chemical Abstracts, vol. 126, abstract No. 14642, 1996.
Blin et al, Chemical Abstracts, vol. 125, abstract No. 212567, 1996.
Haapalinna Antti
Sallinen Jukka
Savola Juha-Matti
Scheinin Mika
Viitamaa Timo
Haapalinna Antti
Jarvis William R. A.
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