Method for the treatment of calcifying pancreatitis

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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A61K 3142

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active

045173095

ABSTRACT:
Method for the treatment of calcifying pancreatitis which comprises administering an effective amount of trimethadione or dimethadione to a patient suffering from calcifying pancreatitis, by which pancreatic stones are effectively dissolved out.

REFERENCES:
patent: 3709895 (1973-01-01), Kohlhaupt et al.
patent: 4183960 (1980-01-01), Asher et al.
patent: 4367234 (1983-01-01), Schnur
Konishi et al., "Experimental Pancreatolithiasis in the Dog", Surgery 89(6):687-691, (1981).
A. Noda et al., "Trimethadione (Troxidone) Dissolves Pancreatic Stones", The Lancet, 1984, 351-353.
Chem. Abstracts, 90(23):179861q, (1979).
Noda et al., "Pancreatolithiasis and Pancreatic Carcinoma", Arch. Intern. Med., vol. 137, 754-760, Jun. 1977.
Noda et al., "Clinical Evaluation of Pancreatic Excretion Test with Dimethadione and Oral BT-PABA Test in Chronic Pancreatis", Digestive Diseases and Sciences, vol. 28, 230-235, Mar. 1983.
Sarles et al, "Treatment of Chronic Calcifying Pancreatitis by Oral Long-Term Administration of Citrate. Preliminary Results", Gastroenterol. Clin. Biol. (Paris) 3, 615-620, (1979).

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