Drug – bio-affecting and body treating compositions – Topical body preparation containing solid synthetic organic... – Anti-inflammatory or anti-irritant
Patent
1993-09-10
1997-10-28
Webman, Edward J.
Drug, bio-affecting and body treating compositions
Topical body preparation containing solid synthetic organic...
Anti-inflammatory or anti-irritant
424 7804, 424449, 514826, 514887, A61K 31765, A61K 31785, A61K 3800, A61M 3700
Patent
active
056815557
ABSTRACT:
A method is provided for treating a hypersensitivity disease comprising parenterally administering to a human afflicted with such a disease an amount of an anionic polymer effective to counteract the symptoms of a disease selected from the group consisting of bronchial asthma, eosinophil-associated nasal inflammation and vernal conjunctivitis, by counteracting the effect of at least one cationic toxin released by the eosinophils of said human.
REFERENCES:
patent: 3074852 (1963-01-01), Mayron
patent: 3202557 (1965-08-01), Kaufman
patent: 3330729 (1967-07-01), Johnson
patent: 3608063 (1971-09-01), Banker
patent: 4021387 (1977-05-01), Goetzl et al.
patent: 4226848 (1980-10-01), Nagai et al.
patent: 4322402 (1982-03-01), Ishikawa et al.
patent: 4623723 (1986-11-01), Keller et al.
patent: 4795436 (1989-01-01), Robinson
patent: 4816449 (1989-03-01), Hahn
patent: 4937232 (1990-06-01), Bell et al.
patent: 5000936 (1991-03-01), Chibret
patent: 5003011 (1991-03-01), Coy et al.
patent: 5036056 (1991-07-01), Kludas
patent: 5100672 (1992-03-01), Gueret et al.
patent: 5145677 (1992-09-01), von Eichborn et al.
patent: 5198350 (1993-03-01), Horisberger et al.
patent: 5200177 (1993-04-01), Leung et al.
patent: 5250293 (1993-10-01), Gleich
patent: 5324510 (1994-06-01), Wegner et al.
The Merck Index, 11th ed., p. 1243.
Gleich, G. L., et al., "Physiochemical and Biological Properties of the Major Basic Protein from Guinea Pig Eosinophil Granules," J. Exp. Med., 140, 313-332 (1974).
Gray, P. W., et al., "Interferon-.gamma.," In: Human Cytokines--Handbook for Basic and Clinical Research, Aggarwal, B. B., et al., (eds.), Blackwell Scientific Publications, Boston, pp. 30-45 (1992).
Kelker, H. C., et al., "Effects of Glycosidase Treatment on the Physicochemical Properties and Biological Activity of Human Interferon-.gamma.," J. Biol. Chem., 258, 8010-8013 (1983).
Sano, E., et al., "Constitutive Long-Term Production and Characterization of Recombinant Human Interferon-Gammas from Two Different Mammalian Cells," Cell Structure and Function, 13, 143-159 (1988).
"Actimmune," 1993 Physicians' Desk Reference, Edition 47, pp. 1078-1079 (1993).
J.P. Arm et al., "The Pathobiology of Bronchial Asthma", Adv. Immunol., 51, 323-382 (1992).
S.M. Berg et al., "Pharmaceutical Salts", J. Pharm. Sci., 66, 1-19 (1977).
C.J. Corrigan et al., "T cells and eosinophils in the pathogenesis of asthma", Immunology Today, 13, 501-507 (1992).
P.J. Mauser et al., "The Effect of Anti-IL-5 on Antigen-Induced Airway Hyperreactivity and Pulmonary Eosinophilia in Guinea Pigs", Am. Rev. Resp. Dis., 145, A859, 1992.
N. Wallen et al., "Glucocorticoids Inhibit Cytokine-Mediated Eosinophil Survival", J. Immunol., 147, 3490-3495 (Nov. 15, 1991).
A.D. Fryer et al., J. Clin. Invest., 90, 2292 (1992).
D.B. Jacoby et al., J. Clin. Invest., 91, 1314 (1993).
P.F. Weller et al., Am. J. Pathol., 100, 793 (1980).
E.J. Goetzl et al., Arch. Pathol., 99, 1 (1975).
R.H. Gundel et al., J. Clin. Invest., 87, 1470 (1991).
R.L. Barker et al., J. Clin. Invest., 88, 798 (1991).
G.J. Gleich et al., J. Allergy Clin. Immunol., 81 776 (1988).
Anionic Polymeric Drugs, L.G. Donaruma et al., eds., Wiley-Interscience, NY (1980) (Chapters 5 and 8).
R.L. Barker et al., FASEB J., 4, A1699, Abstr. 26 (Apr. 26, 1990).
R.M. Ottenbrite, in Anionic Polymeric Drugs, pp. 1-47, L.G. Donamura et al., eds., Wiley Interscience (1980).
A.G. Ellis et al., J. Med. Sci. 136: 407-429 (1908).
B.R. Horn et al, N. Engl. J. Med. 292: 1152-1155 (1975).
G.J. Gleich, J. Exp. Med. 137: 1459-1471 (1973).
T.L. Wasmoen et al., J. Biol Chem. 263: 12559-12563 (1988).
G.J. Gleich, Adv. Immunol. 39: 177-253 (1986).
E. Frigas et al., Lab. Invest. 42: 35-43 (1980).
G.J. Gleich, J. Immunol. 123: 2925-2927 (1979).
M.S. Dunnill, J. Clin. Path. 13: 27-33 (1960).
E. Frigas, Mayo Clinic. Proc. 56: 345-353 (1981).
W. Filley et al., Lancet 2: 11-16 (1982).
S. Motojima et al., Am. Rev. Respir. Dis. 139: 801-805 (1989).
N.J. Gross et al., in Allergy, Principles and Practice, (3rd ed.), vol. I, pp. 792-808 (see at p. 790), E. Middleton, Jr. et al., eds. (1988).
A.J. Wardlaw et al., Am. Rev. Resp. Dis. 137: 62-69 (1988).
R.H. Gundel et al., J. Appl. Physiol. 68: 779-786 (1990).
G.H. Ayars et al., in Am. Rev. Resp. Dis. 140: 125-131 (1989).
R. Bascom et al., in J. Allergy Clin. Immunol. 84: 338-346 (1989).
I.J. Udell et al., in Am. J. Ophthamol. 92: 824-828 (1981).
S.D. Trocme et al., in Am. J. Ophthamol. 108: 57-63 (1989).
Anionic Polymeric Drugs, L.G. Donaruma et al., eds., Wiley-Interscience (1980). A copy of the Table of Contents of this reference book is enclosed.
C. D. Wegner et al., Respir. Physiol 55: 47 (1984).
E.M. Hodnett et al., J. Med. Chem. 21: 652-657 (1978).
D. S. Breslow, in Am. Chem. Soc. Symposium Series 195: 1-9 (1982).
E. Frigas et al., J. Allergy Clin. Immunol. 77: 527-537 (1986).
G.J. Gleich, Hospital Practice, Mar. 15, 1988: 137-160 (1988).
G.J. Gleich et al., J. Allergy and Clin. Immunol. 81: 776-781 (1988).
N.R. Slifman et al., in Allergy Principles and Practice (3rd ed.), vol. I, pp. 179-205, E. Middleton, Jr., et al., eds. (1988).
G.J. Gleich, J. Allergy and Clin. Immunol. 85: 422-436 (1990).
P.L. DeAngelis et al., Biochim. et Biophys. Acta 1037: 100-105 (1990).
Ahmed et al., The New England Journal of Medicine, 329, 90 (1993).
Lane et al., The New England Journal of Medicine, 329, 129 (1993).
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