Method for the treatment of bacterial eye infections

Details Method for the treatment of bacterial eye infections Method for the treatment of bacterial eye infections

2005-04-05

2005-04-05

Prats, Francisco (Department: 1651)

Drug, bio-affecting and body treating compositions

Enzyme or coenzyme containing

C424S093600, C435S195000, C435S183000

Reexamination Certificate

active

06875431

ABSTRACT:
A method for treatment of bacterial infections of the eye is disclosed which comprises a lytic enzyme composition specific for the infecting bacteria, and a carrier for delivering said lytic enzyme. The composition may be in the form of an isotonic solution.

REFERENCES:
patent: 2019789 (1935-11-01), Mahannah
patent: 2315260 (1943-03-01), Lancaster
patent: 2763931 (1956-09-01), McMillan
patent: 3465445 (1969-09-01), Fisher
patent: 3622677 (1971-11-01), Short et al.
patent: 3852424 (1974-12-01), Gaeumann et al.
patent: 3929994 (1975-12-01), Hirsch et al.
patent: 3983209 (1976-09-01), Schmitt
patent: 4062941 (1977-12-01), Davies
patent: 4115546 (1978-09-01), Vidra et al.
patent: 4116327 (1978-09-01), Eglinton et al.
patent: 4122158 (1978-10-01), Schmitt
patent: 4313734 (1982-02-01), Leuvering
patent: 4355022 (1982-10-01), Rabussay
patent: 4361537 (1982-11-01), Deutsch et al.
patent: 4369308 (1983-01-01), Trubiano
patent: 4459361 (1984-07-01), Gefter
patent: 4497900 (1985-02-01), Abram et al.
patent: 4521252 (1985-06-01), Miyake et al.
patent: 4552839 (1985-11-01), Gould et al.
patent: 4707543 (1987-11-01), Zollinger et al.
patent: 4713249 (1987-12-01), Schroder
patent: 4742981 (1988-05-01), Converse
patent: 4784948 (1988-11-01), Scott et al.
patent: 4812445 (1989-03-01), Eden et al.
patent: 4847199 (1989-07-01), Snyder et al.
patent: 4885163 (1989-12-01), Shaar et al.
patent: 4933185 (1990-06-01), Wheatley et al.
patent: 4948726 (1990-08-01), Longoria
patent: 4957686 (1990-09-01), Norris
patent: 5079174 (1992-01-01), Buck et al.
patent: 5108758 (1992-04-01), Allwood et al.
patent: 5120643 (1992-06-01), Ching et al.
patent: 5162226 (1992-11-01), Beachey et al.
patent: 5260292 (1993-11-01), Robinson et al.
patent: 5294369 (1994-03-01), Shigekawa et al.
patent: 5352588 (1994-10-01), Fischetti et al.
patent: 5360617 (1994-11-01), Gasson
patent: 5372931 (1994-12-01), Friedman et al.
patent: 5384265 (1995-01-01), Kidwell et al.
patent: 5393658 (1995-02-01), Olsen
patent: 5479732 (1996-01-01), Burtch et al.
patent: 5500350 (1996-03-01), Baker et al.
patent: 5514602 (1996-05-01), Brooks, Jr. et al.
patent: 5556944 (1996-09-01), Fischetti et al.
patent: 5571667 (1996-11-01), Chu et al.
patent: 5587288 (1996-12-01), Cheung et al.
patent: 5602040 (1997-02-01), May et al.
patent: 5604109 (1997-02-01), Fischetti et al.
patent: 5604110 (1997-02-01), Baker et al.
patent: 5605793 (1997-02-01), Stemmer
patent: 5616686 (1997-04-01), Fischetti et al.
patent: 5643767 (1997-07-01), Fischetti et al.
patent: 5688501 (1997-11-01), Merril et al.
patent: 5707822 (1998-01-01), Fischetti et al.
patent: 5723303 (1998-03-01), Fischetti et al.
patent: 5741487 (1998-04-01), Asai et al.
patent: 5760026 (1998-06-01), Blackburn et al.
patent: 5763251 (1998-06-01), Gasson
patent: 5786205 (1998-07-01), Fischetti et al.
patent: 5821088 (1998-10-01), Darzins et al.
patent: 5840314 (1998-11-01), Scott et al.
patent: 5882631 (1999-03-01), Suga et al.
patent: 5910441 (1999-06-01), Rocha et al.
patent: 5968763 (1999-10-01), Fischetti et al.
patent: 5976792 (1999-11-01), Cheung et al.
patent: 5985271 (1999-11-01), Fischetti et al.
patent: 5985654 (1999-11-01), Fischetti et al.
patent: 5997862 (1999-12-01), Fischetti et al.
patent: 6017528 (2000-01-01), Fischetti et al.
patent: 6056954 (2000-05-01), Fischetti et al.
patent: 6056955 (2000-05-01), Fischetti et al.
patent: 6083684 (2000-07-01), Gasson
patent: 6113887 (2000-09-01), Mori et al.
patent: 6132970 (2000-10-01), Stemmer
patent: 6159688 (2000-12-01), Borchert et al.
patent: 6177554 (2001-01-01), Woo et al.
patent: 6187757 (2001-02-01), Clackson et al.
patent: 6190659 (2001-02-01), Pancholi et al.
patent: 6238661 (2001-05-01), Fischetti et al.
patent: 6248324 (2001-06-01), Fischetti et al.
patent: 6254866 (2001-07-01), Fischetti et al.
patent: 6264945 (2001-07-01), Fischetti et al.
patent: 6277399 (2001-08-01), Fischetti et al.
patent: 6326002 (2001-12-01), Fischetti et al.
patent: 6331405 (2001-12-01), Rambukkana et al.
patent: 6335012 (2002-01-01), Fischetti et al.
patent: 6355477 (2002-03-01), Fischetti et al.
patent: 0293249 (1988-11-01), None
patent: 0359873 (1990-03-01), None
patent: 0 510 907 (1992-10-01), None
patent: 0510907 A 2 (1992-10-01), None
patent: 587541 (1994-03-01), None
patent: 0646646 (1995-04-01), None
patent: 2357246 (1978-02-01), None
patent: WO-9323544 (1993-11-01), None
patent: WO-9531562 (1995-11-01), None
patent: WO 96 07329 (1996-03-01), None
patent: WO-9607329 (1996-03-01), None
patent: WO 97 02351 (1997-01-01), None
patent: WO-9702351 (1997-01-01), None
patent: WO 99 04809 (1999-02-01), None
patent: WO-9904809 (1999-02-01), None
patent: WO 03024410 (2003-03-01), None
Reisenger, et al. (1998) “Characterization ofEscherichia colilysis using a family of chimeric E-L Genes”Fems Microbiol Letter.164(1) p. 159-167.
Sheehan MM, et al, (1997) “The lytic enzyme of the Pneumococcal Phage Dp-I: a chimeric lysis of intergeneric origin.”Mol. Microbiol.25(4) p. 717-725.
Young et al. (2000) “Phages will out: stragegies of host cell lysis.”Trends in Microbiology,8(4) p. 120-127.
Garcia et al.(1997) “The Pneumococcal cell wall degrading enzymes: A modular design to create new lysins?”Microb. Drug Resist.3(2):p. 199-211.
Sheehan MM, et al., (1997) “The Lytic Enzyme of the Pneumococcal Phage Dp-I: a Chimeric Lysin of Intergeneric Origin”Mol. Microbiol.25(4) p. 717-25.
Garcia P, et al. (1997) “Bacteriophages ofStreptococcus pneumoniae:a molecular approach”Microb. Drug Resist.3(20) 165-76.
Sheehan, MM, et al.(1996) “Analysis of the catalytic domain of the lysin of the lactococcal bacteriophage Tuc2009 by chimeric gene assembling.”FEMS Microbiol.Lett.14(1): p. 23-28.
Sanz, JM, et al. (1996) “Construction of a multifunctional pneumococcal murein hydrolase by module assembly.”Eur. J. Biochem.235(3):601-5.
Lopez R, et al. (1995) “Architecture and Domain Interchange of the Pneumococcal Cell Wall Lytic Enzymes”Dev. Biol. Stand.85 p. 273-81.
Croux, et al.(1993) “Interchange of Functional Domains Switches Enzymes Specificity: Construction of a chimeric pneumococcal-clostridial cell wall lytic enzyme.”Mol. Microbiology.9(5) p. 1019-25.
Diaz, E. et al. (1990) Chimeric phage-bacterial enzymes: a clue to the modular evolution of genes.PNAS.87(20) p. 8125-9.
Diaz, E. et al.(1990) “Chimeric pneumoccal cell wall lytic enzymes reveal important physiological and evolutionary traits.”J. Biol. Chem.266(9) p. 5464-71.
Lopez, et al. (1997) “The pneumococcal cell wall degrading enzymes: A modular design to create new lysins?”Microbiological Drug Resistance,3(2) p. 199-211.
Loessner, et al. (1999) “Evidence for a holin-like protein gene fully embedded out of frame in the endolysin gene ofStaphylococcus aureusBacteriophage.” (1999)Journal of Bacteriology,181(15) p. 4452-4460.
Witte, A et al. (1998) “Characterization ofEscherichia colilysis using a family of chimeric E-L genes.”FEMS Microbiol. Lett.,164(1), p. 159-167.
Martin, Ana C et al (1998): “Functional analysis of the two-gene lysis system of the pneumococcal phage Cp-1 in homologous and heterologous host cells.”Journal of Microbiology180(2), p. 210-217.
Oki Masaya et al. (1997) “Functional and structural features of the holin HOL protein of theLactobacillus plantarumphage phi-gle: Analysis inEscherichia colisystem.”Gene(Amsterdam) 1:97(1-2) p 137-145.
Young, Ry et al. (2000) “Phages will out: strategies of host cell lysis.”Trends in Microbiology,8(3) p 120-127.
Nelson, et al. (2001) “Prevention and elimination of upper respiratory colonization of mice by Group A Streptococci by using a bacteriophage lytic enzyme.”PNAS.98 (7) p. 4107-4112.
Garcia, et al. (1987) “Purification and biochemical characterization of the pneumococcal bacteriophage Cp-1 lysin.”Journal of Virology61(8) p. 2573-2580.
Loessner, et al. (1996) “Modified Listeria bacteriophage lysin gene (

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