Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1997-02-06
1998-07-28
Krass, Frederick
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514 17, 514 18, 514212, A01N 4346, A61K 3155
Patent
active
057863261
ABSTRACT:
A method for the treatment of atherosclerosis and vascular injury using exochelins, and more particularly exochelins of Mycobacterium tuberculosis, to prevent vascular smooth muscle cell proliferation. Delivery of an effective amount of a desferri-Exochelins to a living organism such as an animal or a human by oral, intravenous or direct delivery to the site at which the effect is desired will protect blood vessels in a living organism from restenosis following angioplasty or vascular surgery and will prevent or slow the progression of atherosclerosis, systemic hypertension, radiation damage to the vasculature, stenosis or closure of bypass grafts to the coronary arteries or other blood vessels following a surgical procedure and various forms of pulmonary hypertension.
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Kleinberg Marvin H.
Krass Frederick
Lerner Marshall A.
Ram Michael J.
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