Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1990-12-20
1992-11-24
Waddell, Frederick E.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
A61K 31505
Patent
active
051661586
ABSTRACT:
Treatment of apnea and/or bradycardia employing 5-ethyldihrdo-5-phenyl-4,6-[1H,5H]-pyrimidenedione (primidone).
REFERENCES:
Daley, R. D., Anal. Prof. Drug Subst., 2: 409-37 (1973) (Chemical Abstracts 79 (8) 45858h).
Kjellin et al., 1982, Chem. Abs. 96 (17): 142881u. 3,8-Dialkylxanthines compositon and methods for the treatment of chronic obstructive airway disease & cardiovascular diseases.
Hamilton 1987, Chem. Abs. 107 (7) 59053a. Pyrazolo[4,3-d]pyrimidine-5,7-[4H,6H]dione or -5-thione-7-one analogs.
Singh et al., 1986, Chem. Abs. 105 (23): Synthesis of novel pyrimidine diones and thiazolidinones as cardiovascular agents.
Gaylord Mark S.
Lorch Vichien
Miller Christopher A.
Zimmerman Andrew W.
Gardner Diane
The University of Tennessee Research Corporation
Waddell Frederick E.
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