Method for the treatment of aging or photo-damaged skin

Details Method for the treatment of aging or photo-damaged skin Method for the treatment of aging or photo-damaged skin

1988-11-14

1990-07-03

Robinson, Douglas W.

Drug, bio-affecting and body treating compositions

Inorganic active ingredient containing

Heavy metal or compound thereof

424641, 514474, 514567, 514847, A61K 3332, A61K 3134, A61K 31195

Patent

active

049389696

ABSTRACT:
A composition for reducing the depth or intensity of fine wrinkles in skin affected by intrinsic or photo-induced aging is described. The topical formulation comprises in combination ascorbic acid, tyrosine and a non-toxic zinc salt and is preferably formulated in a hydrophilic ointment or cream base.

REFERENCES:
patent: 4668516 (1987-05-01), Duraffourd et al.
patent: 4704280 (1987-11-01), Bates
patent: 4743442 (1988-05-01), Raaf et al.
"Aging-Related Skin Changes: Development and Clinical Meaning", Richey, M. L., Richey, H. K., Fenske, N. A., Geriatrics, vol. 43, No. 4, Apr. 1988, pp. 49-61.
"Handbook of The Biology of Aging", Finch & Schneider, eds. 1985, Van Nostrand Reinhold Company, New York, pp. 825-838.
"Topical Tretinoin Improves Photoaged Skin", Weiss, et al., Jama, Jan. 22/29, 1988, vol. 259, No. 4, pp. 527-532.
"Oral Zinc Therapy in Geriatric Patients with Selected Skin Manifestations and a Low Plasma Zinc Level", Weismann, et al., Acta Dermatovener, 58: 1978, pp. 157-161.

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