Method for the therapeutic management of endometriosis

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

Reexamination Certificate

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C514S013800, C514S014800, C514S015800, C514S016700, C514S017400, C514S018700, C514S019300, C514S252190, C514S260100, C514S274000

Reexamination Certificate

active

07666836

ABSTRACT:
The present inventions provides a method for therapeutic management of extrauterine proliferation of endometrial tissue, chronic pelvic pain and fallopian tube obstruction by short term induction treatment with an LH-RH antagonist for 4 to 12 weeks. According to another aspect of the present invention, the short term LH-RH treatment is followed by the combined or separate administration of one or more active agents selected from the group consisting of a contraceptive, preferably an oral contraceptive, a non-steroidal anti-rheumatic agent, an analgetic, an androgen other than a 17-alpha-alkyl substituted testosterone or any combinations thereof. According to a further aspect of the present invention a pharmaceutical composition comprising an LHRH antagonist and one ore more active agents selected from the group consisting of a contraceptive, preferably an oral contraceptive, a non-steroidal anti-rheumatic agent, an analgetic, an androgen other than a 17-alpha-alkyl substituted testosterone or any combinations thereof are provided.

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Norman, P., “Cetrorelix, Asta Medica AG”, Current Opinion in Oncologic, Endocrine & Metabolic Investigational Drugs, vol. 2, No. 2, pp. 227-248, XP-00982761, 2000.
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