Method for the synthesis of nucleotide or oligonucleotide phosph

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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536 231, 536 267, 536 268, 536 70, C07H 2102, C07H 1910, C07H 1920, C07H 2104

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061038911

ABSTRACT:
The present invention presents novel methods for recovery of phosphoramidites from the waste products of oligonucleotide synthesis. The methods include reacting a trihalophenoxydihalophosphorane with a H-phosphonate in the presence of an amine.

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