Method for the suppression of an immune response

Details Method for the suppression of an immune response Method for the suppression of an immune response

1993-05-24

1994-10-25

Kim, Kay K.

Drug, bio-affecting and body treating compositions

Conjugate or complex of monoclonal or polyclonal antibody,...

4241831, 4242801, 424810, A61K 3935, A61K 39385, A61K 3944, A61K 3900

Patent

active

053587103

ABSTRACT:
A method for suppressing the capacity of a mammal to mount an immune response which would be caused by the administration of one or more biologically active foreign proteins, comprising the administration of an immunosuppressively effective amount of a tolerogen corresponding to said foreign protein or proteins, said administration being performed prior to the administration of said protein or proteins.

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Bitoh et al (1993) Cellular Immunol 150: C68-C93.
Handbook of Experimental Immunology 2nd edition Ed. D. M. Weir, Blackwell Scientific Publications, Oxford 1973 p. 35.3.
Sehon, A. H., "Down Regulation of IgE Antibodies by Suppressogenic Conjugates" (1983) Academic Press Japan, Inc. pp. 483-491.
Sehon, A. H., "Modulation of Antibody Responses by Conjugates of Antigens with Monomethoxypolyethylene Glycol", from Immunobiology of proteins and Peptides V, Plenum Publishing Corp, (1989) ed. by M. Z. Atassi pp. 341-351.
Sehon, A. H., "Immunological Strategies for Therapeutic Destruction and HIV-Infected Cells in Asymptomatic Patients", MCR Group for Allergy Research. pp. 570-574 Progression Allergy and Clin. Immunology, Proceedings 35th Int.Cong. Aller.
Sehon, A. H., "Potential use of Allergens Modified with Monomethoxypolyethylene Glycol for Immunotherapy of Atopic Patients", pp. 313-319, in the Proc. XII International Congress of Allergology and Clin. Immunol. 1986.

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