Method for the stereo-selective preparation of a derivative of .

Details Method for the stereo-selective preparation of a derivative of . Method for the stereo-selective preparation of a derivative of .

1997-11-10

2000-09-05

Trinh, Ba K.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

549511, 560 27, 560 45, 562406, 562450, C07D30514, C07C 5106, C07C22908, C07C27100

Patent

active

061145505

ABSTRACT:
A .beta.-phenylisoserine derivative of general formula (I): ##STR1## in the form of a salt or an ester, in which Ar represent an aryl radical, R represents a phenyl or naphthyl or a O--R.sub.1 radical and G.sub.1 represents --CH.sub.2 --Ph radical; and a method of using the same for making taxane derivatives.

REFERENCES:
patent: 4924011 (1990-05-01), Denis et al.
patent: 5684175 (1997-11-01), Sisti et al.
McOmie J.F, "Protective Groups in Organic Chemistry", Plenum Press, pp. 98-100 (1973).
Greene et al., "Protective Groups in Organic Synthesis" (2d Ed.), John Wiley & Sons, Inc., pp. 10-53 and 410-420 (1991).

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