Method for the separation of protein-bound substances from a pro

Details Method for the separation of protein-bound substances from a pro Method for the separation of protein-bound substances from a pro

1995-12-12

1998-04-28

Kim, John

Liquid purification or separation

Processes

Liquid/liquid solvent or colloidal extraction or diffusing...

210644, 210646, 436177, 436178, B01D 6124

Patent

active

057440425

ABSTRACT:
The present invention provides a process of separating substances bound to a first protein in a first liquid by means of a membrane separating the first liquid from a second liquid, the process comprising the steps of: a) impregnating the membrane by passing along the membrane a solution comprising a first acceptor protein having an acceptor function for the substances to be separated; b) dialyzing the first liquid against the second liquid, the second liquid comprising a second acceptor protein having an acceptor function for the substances to be separated, wherein the membrane separating the first and second liquids contains tunnel-like structures that permit passage of the substances to be separated to the second liquid but exclude passage of the first protein and the second acceptor protein.

REFERENCES:
patent: 4163714 (1979-08-01), Gregor
patent: 4352884 (1982-10-01), Nakashima et al.
patent: 4375414 (1983-03-01), Strahilevitz
patent: 4714556 (1987-12-01), Ambrus et al.
patent: 4741832 (1988-05-01), Leonard
patent: 4874522 (1989-10-01), Okamoto et al.
patent: 5078885 (1992-01-01), Matsumura
patent: 5167824 (1992-12-01), Cohen et al.
patent: 5328614 (1994-07-01), Matsumura

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