Method for the quantitative determination of glycated proteins

Details Method for the quantitative determination of glycated proteins Method for the quantitative determination of glycated proteins

1995-07-17

1997-05-20

Gitomer, Ralph

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving hydrolase

435 24, C12Q 134

Patent

active

056311400

ABSTRACT:
Method for the quantitative determination of glycated protein in particular haemoglobin and HbA1c, wherein the respective sample is firstly contacted with a proteolytic enzyme and subsequently a non-immunological chromatographic separation process is carried out.

REFERENCES:
patent: 4727036 (1988-02-01), Knowles et al.
patent: 5370990 (1994-12-01), Staniford et al.
Landin, B., Rare Beta Chain Hemoglobin Variants Found in Swedish Patients During HBA1c Analysis, Hemoglobin, 17(4) 303-318 1993.
Schluter, M., Isolation of Glycopeptides Containing Individual glycosylation Sites of Friend Murine Leukemia Virus Glycoprotein, 138 305-314 1985. .
Hemoglobin vol. 17, No. 4, Apr. 1993, "Rare .beta.-Chain Hemoglobin Variants found in Swedish Patients During HbAlc Analysis".
Carbohydr. Res. (1985), 138(2), 305-14, "Isolation of glycopeptides containing individual glycopeptides by methylation analysis".
"Arbeitsanleitung Klinische Chemie", 1992. By Merck, Diagnostica (German).

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