Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Hydrolase
Patent
1996-02-05
1998-03-24
Knode, Marian C.
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Hydrolase
435 691, 435 94, 435215, 435216, 435226, 530380, C12N 948, C12N 950, C12N 968, C12P 2106
Patent
active
057311862
ABSTRACT:
rDSPA .alpha.1 is produced in commercial quantities and a purity adequate for clinical standards. The production methods utilize a series of chromatographic steps: cation exchange chromatography, followed by hydrophobic interaction chromatography, and ending with affinity chromatography.
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McCaman Michael
Pungor Erno
Souders Carol
Tan Mei P.
Knode Marian C.
Schering Aktiengesellschaft
Washtien Wendy L.
Zeman Mary K.
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