Drug – bio-affecting and body treating compositions – Plant material or plant extract of undetermined constitution...
Reexamination Certificate
2006-07-11
2006-07-11
Tate, Christopher R. (Department: 1655)
Drug, bio-affecting and body treating compositions
Plant material or plant extract of undetermined constitution...
C424S195180
Reexamination Certificate
active
07074436
ABSTRACT:
A method for the production of an extract ofPhyllanthuswherein (a)Phyllanthuscomponents are extracted with an ethanol/water mixture of 5–85% m/m to which a heavy-metal chelator is added at a concentration of 0.001–3% m/m; (b) the primary extract obtained in step (a) is contacted and concentrated with (ba) Indian Sterculia gum at a final concentration of 0.5–5.0% mm relative to the sum of the extractive substances or (bb) one or more polymers and impendable and/or soluble substance(s); and (c) the concentrated extract obtained in step (b) is dried. The method according to the invention leads to particularly high yield of pharmaceutically effective plant ingredients and is thus of particular interest for therapeutic applications. In a preferred embodiment of the invention the method according to the invention includes a filtration step of the primary extract. It is further preferred that a lipoid is added during the extraction method. ThePhyllanthus Phyllanthus amarusis preferred. Moreover, the invention relates to pharmaceutical compositions containing the extracts obtained by the method of the invention.
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Kreuter Matthias-Heinrich
Tittel Gerolf
Wagner Hildebert K. M.
Baker & Botts L.L.P.
Phytrix, Inc.
Tate Christopher R.
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