Method for the production of oxazoles by condensing aromatic...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C548S215000, C548S235000

Reexamination Certificate

active

07825144

ABSTRACT:
The invention is related to a process for preparing compounds of the formula IV by means of conversion of aromatic aldehydes of the formula I using α-ketoximes of the formula II via N-oxides of the formula III to halomethyloxazoles of the formula IV,wherein R1, R2, R3, R4, R5, R6, R7, R8, X1, X2, X3, o, n1 and n2 are as defined herein.

REFERENCES:
patent: 5036079 (1991-07-01), Clark et al.
patent: 7544809 (2009-06-01), Holla et al.
patent: WO 02/16332 (2002-02-01), None
patent: WO 02/100403 (2002-12-01), None
patent: WO 2004/075815 (2004-09-01), None
patent: WO 2004/076426 (2004-09-01), None
Bodendorf et al (1965): STN International HCAPLUS database, Columbus (OH), accession No. 1965: 431655.
Palmer, D. C., et. al., Synthesis and Reactions of Oxazoles, The Chemistry of Heterocyclic Compounds, vol. 60, Oxazoles: Synthesis, Reactions, and Spectroscopy, Part A, (2003), pp. 1-390.

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