Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acids and salts thereof
Patent
1984-02-07
1984-12-04
Reamer, James H.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carboxylic acids and salts thereof
C07C 9900
Patent
active
044865970
ABSTRACT:
The present invention provides an improved method for producing a nuclear substituted cinnamoylanthranilic acid compound.
Illustrative of the process is the reaction of 3,4-dimethoxybenzaldehyde with 2-carboxymalonanilic acid in an inert solvent medium in the presence of piperidine to provide an intermediate salt precipitate, and the salt is treated with an acidic reagent to yield N-(3,4-dimethoxycinnamoyl)anthranilic acid product.
REFERENCES:
patent: 3755603 (1973-08-01), Harrison et al.
patent: 4337270 (1982-06-01), Noda et al.
Harada Hiromu
Iizuka Kinji
Kamino Tetsuhide
Yamamoto Ryoji
Kissei Pharmaceutical Co. Ltd.
Reamer James H.
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