Method for the production of non-group C adenoviral vectors

Details Method for the production of non-group C adenoviral vectors Method for the production of non-group C adenoviral vectors

1997-05-22

1998-12-15

Ketter, James

Chemistry: molecular biology and microbiology

Virus or bacteriophage, except for viral vector or...

C12N 701

Patent

active

058495614

ABSTRACT:
A method of producing a replication deficient adenovirus comprising a passenger gene and a deficiency in an essential gene function of the E1 region of an adenovirus comprising producing the adenovirus in a cell that provides in trans gene functions of the E1 and E4 regions of one or more adenoviruses not belonging to the same serogroup as the replication deficient adenovirus.

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